Nucleic Acid Sensing in Respiratory Diseases

Dear Colleagues,

Recognition of host cell or pathogen-derived nucleic acids by pattern-recognition receptors (PRRs) is essential to elicit host innate immune responses in numerous contexts such as inflammatory diseases as well as auto-inflammatory or tumor settings. It is a great challenge to review the recent development and include your recent discoveries in the field in this thematic issue of Cells.

Basic aspects of cell stress-induced nucleic acid-sensing and recent developments on mechanisms of nucleic acid-mediated cell activation are welcome. Specifically, we invite studies on inflammatory and infectious diseases in general and include respiratory diseases. Translational considerations and potential novel therapeutic targets will be greatly appreciated.

Dr. Nicolas Riteau
Prof. Dr. Bernhard Ryffel
Dr. Jose C. Alves-Filho
Guest Editors

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