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Children
Special Issues
Viral Respiratory Infections and Bacterial Superinfections in Children
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Viral Respiratory Infections and Bacterial Superinfections in Children

A special issue of Children (ISSN 2227-9067). This special issue belongs to the section "Pediatric Infectious Diseases".

Deadline for manuscript submissions: 20 November 2024 | Viewed by 502

Special Issue Editors

Dr. Victor Daniel Miron

E-Mail
Guest Editor
Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania
Interests: infectious diseases; pediatric infectious diseases; viral diagnostics; viral epidemiology; viral infection; influenza; respiratory syncytial viruses; SARS-CoV-2; respiratory tract infections; pneumococcal infections; bacterial superinfection; medicine based; vaccination; childhood/pediatric obesity
Prof. Dr. Irina Magdalena Dumitru

E-Mail Website
Guest Editor
1. Faculty of Medicine, “Ovidius” University of Constanta, 900470 Constanta, Romania
2. Clinical Infectious Disease Hospital of Constanta, 900178 Constanta, Romania
Interests: infectious diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Viral respiratory infections are exceedingly prevalent among children and represent a significant health concern within the pediatric population. These infections are one of the primary causes for pediatric assessments or for visits to hospital emergency departments. A common concern that often arises in the treatment of these viral infections is the fear of bacterial superinfection. This fear frequently leads to the premature or unnecessary addition of antibiotics to the treatment regimen, a practice that has been shown to contribute markedly to the escalating rates of antimicrobial resistance. Considering this, the purpose of this Special Issue is to cast a spotlight on the clinical and epidemiological characteristics of bacterial superinfections that may occur in the backdrop of various respiratory viral infections such as influenza, respiratory syncytial virus (RSV), and SARS-CoV-2, among others. It is also aimed at gathering and showcasing practical evidence drawn from real clinical cases to better understand these phenomena. Additionally, this issue seeks to provide insight into the bacterial complications that can accompany viral respiratory infections, including conditions like sinusitis, otitis, pneumonia, meningitis, or sepsis. By presenting well-documented evidence and making easy-to-use data available, this Special Issue aspires to be a valuable resource for clinicians. It aims to aid in the effective management of viral respiratory infections complicated by bacterial superinfections, thereby improving patient outcomes and contributing to the fight against antimicrobial resistance.

Dr. Victor Daniel Miron
Prof. Dr. Irina Magdalena Dumitru
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Children is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • viral infections
  • bacterial superinfections
  • respiratory viruses
  • influenza
  • RSV
  • SARS-CoV-2
  • pneumococcal disease
  • otitis, pneumonia, meningitis, sepsis
  • antimicrobial resistance

Published Papers (1 paper)

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Research

10 pages, 455 KiB  
Article
Incidence and Characteristics of Pediatric Patients with Acute Otitis Hospitalized in a Romanian Infectious Diseases Hospital
by Vlad Ștefan Pleșca, Anca Streinu-Cercel, Oana Săndulescu, Anca Cristina Drăgănescu, Răzvan Hainăroșie and Anca Doina Pleșca
Children 2024, 11(7), 832; https://doi.org/10.3390/children11070832 - 8 Jul 2024
Viewed by 78
Abstract
Background: Otic involvement is common in children during acute infectious diseases, and is an important cause of morbidity and health service utilization. Methods: We performed a retrospective analysis of pediatric cases hospitalized in the largest infectious disease hospital in Romania between 2018 and [...] Read more.
Background: Otic involvement is common in children during acute infectious diseases, and is an important cause of morbidity and health service utilization. Methods: We performed a retrospective analysis of pediatric cases hospitalized in the largest infectious disease hospital in Romania between 2018 and 2023, with the aim of quantifying the incidence and impact of acute otitis (AO) according to pediatric age subgroups. Results: A total of 1118 cases diagnosed with AO were eligible and included in the analysis. Acute congestive otitis media was the most common subtype, identified in 53.3% of cases, followed by acute purulent otitis media (APOM) in 26.7% of children. The majority of AO cases (69.9%) were diagnosed in the pre-pandemic period (2018–2019), and infants (10.6%), toddlers (49.4%), and preschoolers (29.2%) were the most affected age groups. A viral infection associated with the AO episode was documented in 49.6% of cases. Influenza viruses were most commonly reported (20.5%), followed by SARS-CoV-2 (5.8%), and adenovirus (4.9%). A total of 38 cases of AO were identified in children with measles. In 15.9% of APOM cases, Streptococcus pneumoniae was isolated by culture from otic secretions. The duration of hospitalization was longer in children with APOM and acute otitis externa compared to the other subtypes of AO (p < 0.001). Conclusions: Our study highlights the importance of ENT (ear, nose, and throat) monitoring in children hospitalized for acute infectious diseases, as the majority of AO cases occur in the context of a viral infection. These findings emphasize the necessity for tailored assessment and intervention in suspected cases of AO, especially in young children under 5 years of age. Full article
(This article belongs to the Special Issue Viral Respiratory Infections and Bacterial Superinfections in Children)
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