Sickle Cell Disease in Children

Dear Colleagues,

It is my pleasure to serve as the Guest Editor for this Special Issue of Children, entitled “Sickle Cell Disease in Children”. Sickle cell disease (SCD) is a widespread and fatal congenital hemoglobinopathy that strikes millions of children around the world and represents a heavy burden for many countries, not only in Africa but also in Europe and the Americas.

Nevertheless, SCD remains a disease that is still frequently unrecognized and has been neglected for too long by public health policies. This is now changing.

Indeed, enormous advances have been made over the last decade, both in understanding the physiopathology of the disease and in the development of new therapeutic options. Many innovative programs are being promoted around the world and at all levels of care: genetic counseling and neonatal screening, access to primary care, therapeutic education, new drug combinations, bone marrow transplants, and soon curative gene therapy. The future of a SCD-child born today will hopefully be much less grim than that of their predecessors.

The aim of this Special Issue is to share new knowledge in the pathophysiology of the disease and in global management of SCD children worldwide.

We invite researchers and physicians to contribute to this Special Issue in the format of original research articles, as well as review articles that will provide readers with an overview of SCD in its current and future management.

We look forward to your participation.

Dr. Berengere Koehl
Guest Editor

Manuscript Submission Information

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