Innovations in Combining SBRT and Systemic Treatments for Urological Cancers

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Genitourinary Oncology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 2487

Special Issue Editor


E-Mail Website
Guest Editor
Department of Radiation Oncology, University of California Irvine, Orange, CA 92868, USA
Interests: stereotactic body radiotherapy; genitourinary oncology; gastrointestinal oncology

Special Issue Information

Dear Colleagues,

Stereotactic Body Radiation Therapy (SBRT) has emerged as a promising treatment modality for urological cancers, offering precise delivery of high-dose radiation to tumors while minimizing damage to surrounding healthy tissues. Systemic treatments, including immunotherapy, chemotherapy, and targeted agents, play a crucial role in combating urological cancers by addressing cancer cells throughout the body. Additionally, ablative radiation (> 45 Gy) delivered in 15-25 courses, though not strictly SBRT, presents another effective treatment approach. The integration of these systemic approaches with SBRT and ablative radiation holds the potential to revolutionize treatment paradigms, offering enhanced therapeutic outcomes and improved quality of life for patients. Covering a spectrum of urological malignancies including prostate, bladder, kidney, and testicular cancers, this issue aims to showcase innovative strategies that integrate SBRT, ablative radiation, and various systemic therapies. By exploring the synergies between localized radiation therapies and systemic treatments, this collection anticipates shedding light on novel approaches that may redefine treatment standards in urologic oncology. Authors are encouraged to submit research that elucidates the potential benefits, challenges, and future directions of combining these radiation therapies with systemic interventions for urological cancers.

Dr. Steven N. Seyedin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Oncology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urological cancers
  • stereotactic body radiation therapy (SBRT)
  • systemic treatments
  • ablative radiation
  • immuno-therapy
  • chemotherapy
  • targeted agents

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

12 pages, 1039 KiB  
Review
Focal Therapy for Prostate Cancer: Recent Advances and Insights
by Francesco Lasorsa, Arianna Biasatti, Angelo Orsini, Gabriele Bignante, Gabriana M. Farah, Savio Domenico Pandolfo, Luca Lambertini, Deepika Reddy, Rocco Damiano, Pasquale Ditonno, Giuseppe Lucarelli, Riccardo Autorino and Srinivas Vourganti
Curr. Oncol. 2025, 32(1), 15; https://doi.org/10.3390/curroncol32010015 - 28 Dec 2024
Viewed by 2185
Abstract
Focal therapy has emerged as a balanced middle ground aiming to reduce overtreatment and the risk of progression, as well as patients’ distress and anxiety. Focal therapy and partial gland ablation prioritize the precise elimination of the index lesion and a surrounding safety [...] Read more.
Focal therapy has emerged as a balanced middle ground aiming to reduce overtreatment and the risk of progression, as well as patients’ distress and anxiety. Focal therapy and partial gland ablation prioritize the precise elimination of the index lesion and a surrounding safety margin to optimize treatment outcomes and lower the risk of residual disease. The paradigm of whole-gland ablation has shifted towards more targeted approaches. Several treatment templates ranging from subtotal and hemiablation to “hockey-stick”, quadrant, and even focal lesion ablation have emerged. Many types of energy may be utilized during focal treatment. First, focal therapy can be grossly classified into thermal vs. non-thermal energy. The aim of this non-systematic review is to offer a comprehensive analysis of recently available evidence on focal therapy for PCa. Full article
Show Figures

Figure 1

Back to TopTop