Innovations in Combining SBRT and Systemic Treatments for Urological Cancers

A special issue of Current Oncology (ISSN 1718-7729). This special issue belongs to the section "Genitourinary Oncology".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 5

Special Issue Editor


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Guest Editor
Department of Radiation Oncology, University of California Irvine, Orange, CA 92868, USA
Interests: stereotactic body radiotherapy; genitourinary oncology; gastrointestinal oncology

Special Issue Information

Dear Colleagues,

Stereotactic Body Radiation Therapy (SBRT) has emerged as a promising treatment modality for urological cancers, offering precise delivery of high-dose radiation to tumors while minimizing damage to surrounding healthy tissues. Systemic treatments, including immunotherapy, chemotherapy, and targeted agents, play a crucial role in combating urological cancers by addressing cancer cells throughout the body. Additionally, ablative radiation (> 45 Gy) delivered in 15-25 courses, though not strictly SBRT, presents another effective treatment approach. The integration of these systemic approaches with SBRT and ablative radiation holds the potential to revolutionize treatment paradigms, offering enhanced therapeutic outcomes and improved quality of life for patients. Covering a spectrum of urological malignancies including prostate, bladder, kidney, and testicular cancers, this issue aims to showcase innovative strategies that integrate SBRT, ablative radiation, and various systemic therapies. By exploring the synergies between localized radiation therapies and systemic treatments, this collection anticipates shedding light on novel approaches that may redefine treatment standards in urologic oncology. Authors are encouraged to submit research that elucidates the potential benefits, challenges, and future directions of combining these radiation therapies with systemic interventions for urological cancers.

Dr. Steven N. Seyedin
Guest Editor

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Keywords

  • urological cancers
  • stereotactic body radiation therapy (SBRT)
  • systemic treatments
  • ablative radiation
  • immuno-therapy
  • chemotherapy
  • targeted agents

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