Microbial Upcycling of Organic Waste to Biofuels and Biochemicals

A special issue of Fermentation (ISSN 2311-5637). This special issue belongs to the section "Industrial Fermentation".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 668

Special Issue Editors

Biomass Energy Engineering Center, Department of Resources and Environment, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China
Interests: biomass energy engineering; waste-to-resource technologies; environmental microbial technologies
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Guest Editor
Biomass Energy Engineering Centre, Department of Resources and Environment, School of Agriculture and Biology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, China
Interests: anaerobic digestion; microbial management of organic wastes; biofuels; lignocellulolytic enzyme production

Special Issue Information

Dear Colleagues,

The management of organic wastes is currently a critical challenge globally. Of specific interest is food waste, agricultural waste, horticultural waste, animal manure, waste-activated sludge, wastewater, algal residues, and other industrial organic residues. Meanwhile, abundant renewable energy and resources remain unharnessed in such organic wastes. Therefore, to overcome the challenge, a large number of studies on microbial fermentation technologies have been conducted to convert various organic wastes to biofuels and biochemicals. For instance, anaerobic digestion of organic wastes can be performed for the production of methane-rich biogas. Acidogenic fermentation of organic wastes can be conducted for the production of carboxylic acids. Fermentation of oleaginous yeast can be carried out for the production of microbial lipids. Additionally, biohydrogen can be obtained through dark fermentation of organic wastes, and polypeptide can be produced from the fermentation of certain pure strains. These studies and related field-scale tests have contributed a lot to improving the sustainability of a circular economy.

To further enhance the process efficiency, studies on some enhancing strategies, such as feedstock pretreatment, microbial bio-augmentation, and supplementation of additives in fermentation bioreactors, have been conducted with promising findings, but the efficiency requires further confirmation in larger-scale fermentation systems. To make the fermentation systems more practical, lifecycle assessment and cost–benefit analysis have been performed to analyze the economic feasibility. The post-treatment of the fermentation liquid also requires more investigation to find the appropriate approaches that can reduce its environmental impacts and treatment cost.

In the global context of circular economy, this Special Issue aims to encourage and advance the research of microbial fermentation technologies for the conversion of various organic wastes into biofuels and biochemicals.

Dr. Le Zhang
Dr. Rouf Ahmad Dar
Guest Editors

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Keywords

  • fermentation
  • organic wastes
  • biochemicals
  • biofuels
  • bioenergy
  • biogas
  • biohydrogen
  • anaerobic digestion
  • acidogenic fermentation
  • dark fermentation

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Published Papers (1 paper)

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Review

28 pages, 1337 KB  
Review
Recent Advances in Microbial Bioconversion as an Approach to Boost Hydroxytyrosol Recovery from Olive Mill Wastewater
by Irene Maria Zingale, Anna Elisabetta Maccarronello, Claudia Carbone, Cinzia Lucia Randazzo, Teresa Musumeci and Cinzia Caggia
Fermentation 2025, 11(8), 477; https://doi.org/10.3390/fermentation11080477 - 20 Aug 2025
Viewed by 561
Abstract
Olive mill wastewater (OMWW) is a highly complex matrix derived from olive oil extraction, containing phenolic compounds, lipids, minerals, and organic acids. Hydroxytyrosol (HT), an outstanding antioxidant and health-promoting phenolic compound, has garnered significant interest as a natural preservative and functional ingredient. Enzymatic [...] Read more.
Olive mill wastewater (OMWW) is a highly complex matrix derived from olive oil extraction, containing phenolic compounds, lipids, minerals, and organic acids. Hydroxytyrosol (HT), an outstanding antioxidant and health-promoting phenolic compound, has garnered significant interest as a natural preservative and functional ingredient. Enzymatic hydrolysis, utilizing purified enzymes to cleave glycosidic or ester bonds, and microbial bioconversion, employing whole microorganisms with their intrinsic enzymes and metabolic pathways, are effective biotechnological strategies for fostering the release of HT from its conjugated forms. These approaches offer great potential for the sustainable recovery of HT from OMWW, contributing to the valorization of this environmentally impactful agro-industrial by-product. Processed OMWW can lead to clean-label HT-enriched foods and beverages, capitalizing on by-product valorization and improving food safety and quality. In this review, the most important aspects of the chemistry, technology, and microbiology of OMWW were explored in depth. Recent trends and findings in terms of both enzymatic and microbial bioconversion processes are critically discussed, including spontaneous and driven fermentation, using selected microbial strains. These approaches are presented as economically viable options for obtaining HT-enriched OMWW for applications in the food and nutraceutical sectors. The selected topics aim to provide the reader with a solid background while inspiring and facilitating future research and innovation. Full article
(This article belongs to the Special Issue Microbial Upcycling of Organic Waste to Biofuels and Biochemicals)
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