Regulation of Gene Expression in Fish

Dear Colleagues,

The growing levels of contaminants associated with human activity such as industry, mining, agriculture, and household waste production create pollution of the aquatic environment worldwide. Fish, as aquatic organisms, accumulate pollutants directly from contaminated water and indirectly via the food chain. Potentially harmful substances (heavy metals, pesticides, polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), etc.) in fish present a major threat to human health.

Recently, gene expression analysis has become the method of choice for many toxicological studies, because toxicant exposure often alters the gene expression profile as cells regulate certain genes to protect cellular structures, while analysis of these gene expression data can provide information regarding contaminant exposure and potential effects at higher biological levels.

The aim of this Special Issue (SI) entitled “Regulation of Gene Expression in Fish” is to provide a platform to present issues about the use of several gene expression profiles, as molecular biomarkers in several species by using several molecular approaches, as northern blotting, real-time quantitative PCR (RT-qPCR), microarrays, next-generation sequencing (NGS), and other molecular methods for measuring gene expression.

In summary, in this SI all studies are welcome, which includes the molecular approaches to measure not only the toxic effects of single compounds, but also toward simple mixtures in laboratory conditions in order to highlight the mechanism responsible for gene expression regulation in fish species.

Dr. Rigers Bakiu
Prof. Dr. Hongyu Ma
Dr. Ahmed Elaswad
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fishes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• biomarker
• aquatic ecosystem
• pollution
• gene expression profile
• transcriptome