Interaction between Endocrine and Immune Systems in Fish
A special issue of Fishes (ISSN 2410-3888).
Deadline for manuscript submissions: closed (30 June 2018) | Viewed by 6912
Special Issue Editor
Interests: oxidative stress; biomarkers; xenobiotics; toxicology; aquatic animals
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Special Issue Information
Dear Colleagues,
Immune systems protect animals from threats by parasites, bacteria, and viruses. Most of what we know today about the composition, function, and regulation of the two fundamental branches of the immune system—innate immunity and adaptive immunity—comes from studies on mammals. However, recently, there has been an increased interest in fish immunology for several reasons. The innate system also plays an instructive role in the acquired immune response and homeostasis and is therefore equally important in higher vertebrates. The innate immune system is a fundamental defense mechanism of fish. Innate immunity provides some form of defense against pathogens in all multicellular organisms both cartilaginous and bony fish. The innate immune system is divided into physical barriers, cellular and humoral components. Humoral parameters include growth inhibitors, several lytic enzymes and components of the complement pathways, agglutinins and precipitins (opsonins, primarily lectins), natural antibodies, cytokines, chemokines and antibacterial peptides. Several external and internal factors can influence the activity of innate immune parameters. Temperature changes, handling and crowding stress can have suppressive effects on innate parameters, whereas several food additives and immunostimulants can enhance different innate factors. Additionally, estrogen can modulate several functions of immune system in teleosts fish via ER-mediated pathways. Knowledge of mechanisms is important for the use and design of vaccines, now so essential for expanding aquaculture industry, whereas studies of fish immunology contribute to the understanding of the evolution of adaptive immunity.
Dr. Caterina Faggio
Guest Editor
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Keywords
- Immune system
- Teleosts fish
- Estrogen receptor
- Cytokines
- Chemokines
- Stress
- Oxidative status
- Phagocytosis
- Endocrine effects
- Cartilagineous fish
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