Zebrafish Pathology and Contaminant Pathological Effects

Dear Colleagues,

The zebrafish (Danio rerio) has been extensively used as an animal model in various fields of biomedical research. Zebrafish peculiarities such as small size, lower cost of housing and breeding systems, high fertility, and short generational intervals, in addition to egg transparency, allow them to be an experimental model for research studies in different topics, such as aging, infectious or inflammatory diseases, developmental biology, phenotype-based drug discovery, and toxicology. Zebrafish genome sequencing outcomes have shown how this small fish shares about 70% of orthologous protein encoding genes with humans. This teleost also has well-conserved structures and molecular mechanisms, particularly gastrointestinal, hematopoietic, neurological, and immunological systems, which is why it is widely used in translational research, particularly as model for neurological disorders, cardiovascular diseases, hematological disorder, muscle disease and cancers, anxiety, Parkinson’s disease, and post-traumatic stress disorder. Moreover, zebrafish embryos are a validated models for fish embryo toxicity test (FET) and developmental studies.

National regulations regarding the identification of environmental hazards caused by chemicals, pharmaceutical products, and nanoparticles are based on tests that use vertebrates such as zebrafish as models.

Potential topics include: zebrafish diseases; congenital anomalies; viral diseases; bacterial diseases; parasitic diseases; zebrafish oncology; immunological studies on zebrafish; pharmacological and toxicological study with attention to pathological effects on zebrafish; health surveillance; and embryogenesis, differentiation, and gene expression in the zebrafish model.

Dr. Carmelo Iaria
Dr. Fabiano Capparucci
Dr. Roberta Pecoraro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Fishes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.