Ultra Performance Liquid Chromatography - Mass Spectrometry: Evaluation and Applications in Food Analysis

A special issue of Foods (ISSN 2304-8158). This special issue belongs to the section "Food Analytical Methods".

Deadline for manuscript submissions: closed (14 November 2022) | Viewed by 3228

Special Issue Editors


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Guest Editor
Department of Sciences and Technological Innovation, University of Piemonte Orientale, Vercelli, Italy
Interests: chemometrics; analytical chemistry; food; cultural heritage; mass spectrometry

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Guest Editor
Department of Sciences and Technological Innovation, University of Piemonte Orientale, Vercelli, Italy
Interests: chemometrics; analytical chemistry; proteomics; multivariate statistical analysis; food; biomarkers identification

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Guest Editor
Department of Sciences and Technological Innovation, University of Piemonte Orientale, Corso Trieste 15/A, I-28100 Novara, Italy
Interests: analytical chemistry; metabolomics; lipidomics; biomarker discovery; chromatography; mass spectrometry
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Special Issue Information

Dear Colleagues,

The use of ultra-high performance liquid chromatography coupled to mass spectrometry (UHPLC-MS) is increasing as a valid method/platform in food science for assessing food quality, safety, and traceability in a robust, efficient, sensitive, and cost-effective way. 

The diffusion of UHPLC-MS instruments opened new frontiers and possibilities for scientists to characterize and determine food proteomes and metabolomes, but also for food authentication and pesticide residue analyses. These qualitative and quantitative analyses can also provide insights into food industrial processes as well as the use of adulteration practices, and the presence of food contaminants.

In addition, the advent of this analytical equipment coupled to chemometric techniques now offers enormous opportunities to obtain detailed information that can be correlated with various food properties and functionalities, which improve the scope of traditional targeted analysis, providing a new opportunity to investigate hitherto unresolved topics and problems in food science.

This Special Issue welcomes scientific contributions and critical reviews that employ the use of ultra-high performance liquid chromatography coupled to mass spectrometry for targeted and untargeted food analysis, as well as new applications in food science, such as applications for food composition, food safety, quality, nutrition, and health.

Prof. Dr. Emilio Marengo
Dr. Elisa Robotti
Dr. Elettra Barberis
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Foods is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • ultra-high performance liquid chromatography
  • mass spectrometry
  • food analysis
  • food metabolomics and proteomics
  • food authentication
  • chemometric techniques

Published Papers (1 paper)

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Research

23 pages, 2563 KiB  
Article
Rapid and High-Throughput Determination of Sixteen β-agonists in Livestock Meat Using One-Step Solid-Phase Extraction Coupled with UHPLC-MS/MS
by Yonghong Yan, Jun Ning, Xin Cheng, Qingqin Lv, Shuang Teng and Wei Wang
Foods 2023, 12(1), 76; https://doi.org/10.3390/foods12010076 - 23 Dec 2022
Cited by 4 | Viewed by 2601
Abstract
β-agonists are illegally added to animal feed because they can greatly increase carcasses’ leanness, which impairs the safety of animal-derived foods and indirectly endangers human health. This study aimed to develop an ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for determining sixteen [...] Read more.
β-agonists are illegally added to animal feed because they can greatly increase carcasses’ leanness, which impairs the safety of animal-derived foods and indirectly endangers human health. This study aimed to develop an ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for determining sixteen β-agonists in livestock meat. The homogenized samples were subjected to enzymatic hydrolysis using β-glucuronidase/sulfatase at 40 °C for 2 h, extracted with acetonitrile containing 1% acetic acid (v/v), and purified by the one-step Qvet-AG extraction column. The residue was redissolved by 0.1% aqueous formic acid/methanol (9:1, v/v) after blow-drying by nitrogen, and then determined by UHPLC-MS/MS. The results demonstrated that the well linearity was in the range of 0.1–50 μg/L with the correlation coefficient (R2) ≥0.9928, and the limits of detection (LOD) and quantification (LOQ) were 0.01–0.11 μg/kg and 0.04–0.38 μg/kg, respectively. With intraday and interday relative standard deviations (RSDs) being less than 10%, the average recoveries of pork, beef, and lamb at various spiked levels ranged from 62.62–115.93%, 61.35–106.34%, and 62.00–111.83%, respectively. In conclusion, the established method is simple, efficient, sensitive, and suitable for the simultaneous detection of several β-agonist residues in livestock meat. Full article
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