Hydrogels, Oleogels and Bigels Used for Drug Delivery

Dear Colleagues,

Semisolid preparations have always been preferred by patients due to their decreased risk of side effects and ease of administration. The selected semisolid formulations in this Special Issue are hydrogels, oleogels, and a combination of these two called bigels (a semisolid form that can provide the same or better properties than the latter two; they are also named viscous emulsions). All three of them can incorporate many active pharmaceutical ingredients (APIs) from different biopharmaceutical classes (BCS I-IV), resulting in homogenous (dissolved in the gel base) or heterogenous dispersions (dispersed as an emulsion or suspended in the gel base) that imply distinctive behaviors regarding permeation through different membranes (natural or synthetic). The size of the dispersed API and the application area can influence permeation through the biological membranes. The way the API remains as a dispersion in the gelled matrix also influences the gel’s structure and its behavior regarding consistency, extensometry, cohesiveness, adhesivity, extrudability, etc. This Special Issue aims to outline the current research on semisolid pharmaceutical formulations, focusing on hydrogels, oleogels, and bigels, and welcomes original and review papers on all the aspects of their design, development, manufacturing, characterization, administration, and use for patient-centered therapy.

Dr. Robert-Alexandru Vlad
Prof. Dr. Adriana Ciurba
Dr. Paula Antonoaea
Prof. Dr. Aline F. Miller
Guest Editors

Manuscript Submission Information

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