Artificial Intelligence in Public Health, Healthcare Services, and Management

A special issue of Healthcare (ISSN 2227-9032). This special issue belongs to the section "Artificial Intelligence in Healthcare".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 4087

Editors


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Guest Editor
Department of Health Sciences, School of Public Health and Health Sciences, College of Health, Human Services and Nursing, California State University, Dominguez Hills 1000 E. Victoria Street, Carson, CA 90747, USA
Interests: transitional sciences; innovation diffusion in health; health system improvement

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Guest Editor Assistant
Department of Health and Human Sciences, Southeastern Louisiana University, Hammond, LA 70402, USA
Interests: health equity; health policy evaluation; public health innovation; behavioral economics in public health; neurodevelopmental disorders

Special Issue Information

Dear Colleagues,

Artificial Intelligence (AI) stands as the third major revolution of the 21st century, after personal computers and the Internet. It is rapidly reshaping the global landscape of public health and healthcare systems. While health is one of the most active frontiers in this revolution, important questions remain: What tangible progress has been made? How effective and efficient is AI in real-world applications? What barriers do health leaders and managers face in adopting, integrating, and scaling AI technologies? And critically, what roles can AI play that we have not yet fully explored?

To harness the full potential of this revolution, we must understand the current landscape—who is leading innovation, where are breakthroughs happening, and what challenges or gaps are hindering progress? We must also explore new, context-specific solutions to accelerate responsible and equitable AI adoption in healthcare.

This Special Issue aims to illuminate the diverse and evolving roles of AI across public health surveillance, clinical decision-making, service delivery, leadership and management, policy implementation, and workforce transformation. We seek to feature interdisciplinary research and applied case studies (basic, operational, and translational) that deepen our understanding of how AI can improve outcomes, boost efficiency, and reduce disparities in healthcare systems worldwide.

We invite original research, reviews, and case reports that provide theoretical insights, practical solutions, ethical reflections, and policy recommendations. Contributions highlighting innovations in low- and middle-income countries (LMICs), underserved communities, and global health systems are especially welcome. Research areas may include (but are not limited to) the following:

  • AI in public health practice, decision-making, and leadership;
  • Disease surveillance and outbreak prediction;
  • Predictive modeling and risk stratification;
  • GenAI in diagnostics, imaging, and EHRs;
  • AI-driven patient engagement and behavior change;
  • Workflow automation and service optimization;
  • Ethics, bias, and equity in AI;
  • Policy frameworks and system-level integration;
  • Case studies, especially from LMICs and resource-constrained settings.

Join us in exploring what is next for AI in health. We look forward to hearing from you.

Dr. Obinna O. Oleribe
Guest Editor

Dr. Florida Uzoaru
Guest Editor Assistant

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence (AI)
  • generative AI (GenAI)
  • public health innovation
  • healthcare management
  • predictive analytics
  • health systems optimization
  • digital health transformation
  • ethics and AI in healthcare
  • global health and equity
  • AI in low- and middle-income countries (LMICs)

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Published Papers (3 papers)

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Research

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27 pages, 588 KB  
Article
Determinants of AI Adoption in Saudi Arabian Healthcare Institutions
by Saeed Ali Al-Shahrani, Zahyah H. Alharbi and Tahani Alqurashi
Healthcare 2026, 14(13), 1833; https://doi.org/10.3390/healthcare14131833 - 24 Jun 2026
Viewed by 329
Abstract
Background/Objectives: Artificial Intelligence (AI) integration in healthcare promises improved diagnostic accuracy, patient safety, and operational efficiency. However, AI acceptance among healthcare workers remains limited due to knowledge gaps, risk concerns, and governance challenges, particularly in developing countries like Saudi Arabia, where rapid healthcare [...] Read more.
Background/Objectives: Artificial Intelligence (AI) integration in healthcare promises improved diagnostic accuracy, patient safety, and operational efficiency. However, AI acceptance among healthcare workers remains limited due to knowledge gaps, risk concerns, and governance challenges, particularly in developing countries like Saudi Arabia, where rapid healthcare modernization faces unique infrastructure, organizational, and cultural challenges. This research investigates the factors influencing AI acceptance among medical practitioners, nurses, administrators, and students in Saudi Arabian hospitals to identify key determinants and barriers to adoption. Methods: This cross-sectional study employed an extended Unified Theory of Acceptance and Use of Technology (UTAUT) framework integrated with ethical considerations from the Model for Ethical Assessment and Analysis of AI in Medicine (MEAAM). A structured bilingual questionnaire was administered to 119 healthcare professionals and students across Saudi Arabia, measuring constructs including Awareness and Knowledge, Performance Expectancy, Effort Expectancy, Facilitating Conditions, Social Influence, Trust, Perceived Risk, Ethical Governance, and Price Value. Partial Least Squares Structural Equation Modeling (PLS-SEM) was employed for quantitative analysis, supplemented by thematic analysis of open-ended qualitative responses. Results: The PLS-SEM analysis explained 59.8% of variance in behavioral intention to adopt AI (R2 = 0.598). Awareness and Knowledge emerged as the strongest predictor (β = +0.505, p < 0.001), followed by Performance Expectancy (β = +0.229, p < 0.05) and Social Influence (β = +0.123). Perceived Risk functioned as the primary barrier (β = −0.185, p < 0.05). Qualitative findings identified infrastructure gaps, regulatory ambiguities, and training deficiencies as major implementation barriers, while emphasizing opportunities in diagnostic accuracy and remote monitoring. Conclusions: AI acceptance in Saudi healthcare is primarily driven by knowledge, with perceived usefulness and peer support as secondary facilitators, while safety and accountability concerns remain substantial obstacles. Successful AI integration requires coordinated efforts in education, transparent governance frameworks, and institutional support. This study contributes theoretically by validating extended UTAUT in a non-Western healthcare context and practically by providing evidence-based strategies for sustainable AI adoption that enhance healthcare quality while respecting professional roles and ethical principles. Full article
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35 pages, 1117 KB  
Systematic Review
Machine Learning-Based Frailty Prediction and Classification in Community-Dwelling Older Adults: A Systematic Review of Validation, Explainability, and Implementation Readiness
by Seungmi Kim, Myung-Jun Shin, Byung Kwan Choi, Zoran Obradovic, Daniel J. Rubin and Jong-Hwan Park
Healthcare 2026, 14(11), 1543; https://doi.org/10.3390/healthcare14111543 - 1 Jun 2026
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Abstract
Background and Objectives: Frailty is a multidimensional vulnerability in older adults; the Fried phenotype and Frailty Index are clinically informative but labor-intensive, limiting scalability for community screening. Machine learning (ML) can model heterogeneous, high-dimensional data, but real-world adoption is constrained by heterogeneity in [...] Read more.
Background and Objectives: Frailty is a multidimensional vulnerability in older adults; the Fried phenotype and Frailty Index are clinically informative but labor-intensive, limiting scalability for community screening. Machine learning (ML) can model heterogeneous, high-dimensional data, but real-world adoption is constrained by heterogeneity in definitions, predictors, validation strategies, and explainability. We systematically synthesized ML-based studies of frailty prediction and classification in community-dwelling older adults, examining validation rigor, explainability, and implementation readiness. Methods: This systematic review followed PRISMA 2020 and was registered in PROSPERO (CRD420251081555). PubMed, Embase, Web of Science, and Scopus were searched on 4 July 2025, with a supplementary IEEE Xplore and ACM Digital Library search conducted on 12 May 2026. Eligible studies included community-dwelling adults aged ≥60 years, ML-based frailty prediction or classification, sample ≥ 1000, and publication in a peer-reviewed journal indexed in the Web of Science Core Collection; hospital-based studies were excluded. Risk of bias and reporting quality were assessed with PROBAST (Prediction Model Risk of Bias Assessment Tool) and TRIPOD (Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis); implementation readiness was assessed with the RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) framework and a Technology Readiness Level (TRL)-style rubric. Findings were synthesized narratively. Results: Fourteen studies (development cohorts 1230–86,133 participants) were included; the supplementary IEEE/ACM search identified 42 records but yielded no additional eligible studies. Classification of current frailty status (n = 7) yielded AUROCs (area under the receiver operating characteristic curve) of 0.70–0.98, with the highest values likely reflecting partial label overlap with frailty components; incident prediction (n = 6) yielded internal AUROCs of 0.70–0.81 and same-cohort temporal AUROCs of 0.58–0.85; independent external validation was uncommon. Only 2 of 14 studies had both low overall risk of bias and low applicability concern (PROBAST); the field is concentrated at TRL 4–6, with no study at TRL 7 or higher and none documenting Implementation or Maintenance domains of RE-AIM. Conclusions: ML-based frailty models show heterogeneous discrimination and limited readiness for routine community use. Priorities include standardized task-type-specific definitions, independent external validation, calibration and decision-curve reporting, transparent predictor disclosure, and prospective implementation evaluation. Full article
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19 pages, 907 KB  
Perspective
Transforming Public Health Practice with Artificial Intelligence: A Framework-Driven Approach
by Obinna O. Oleribe, Florida Uzoaru, Adati Tarfa, Olabiyi H. Olaniran and Simon D. Taylor-Robinson
Healthcare 2026, 14(3), 385; https://doi.org/10.3390/healthcare14030385 - 3 Feb 2026
Cited by 2 | Viewed by 1983
Abstract
Background: The emergence of artificial intelligence (AI) has triggered a global transformation, with the healthcare sector experiencing significant disruption and innovation. In current public health practice, AI is being deployed to power various aspects of public functions, including the assessment and monitoring of [...] Read more.
Background: The emergence of artificial intelligence (AI) has triggered a global transformation, with the healthcare sector experiencing significant disruption and innovation. In current public health practice, AI is being deployed to power various aspects of public functions, including the assessment and monitoring of health, surveillance and disease control, health promotion and education, policy development and planning, health protection and regulation, prevention services, workforce development, community engagement and partnerships, emergency preparedness and response, and evaluation and research. Nevertheless, its use in leadership and management, such as in change management, process development and integration, problem solving, and decision-making, is still evolving. Aim: This study proposes the adoption of the Public Health AI Framework to ensure that inclusive data are used in AI development, the right policies are deployed, and appropriate partnerships are developed, with human-relevant resources trained to maximize AI potential. Implications: AI holds immense potential to reshape public health by enabling personalized interventions, democratizing access to actionable data, supporting rapid and effective crisis response, advancing equity in health outcomes, promoting ethical and participatory public health practices, and strengthening environmental health and climate resilience. Achieving this goal will require a deliberate and proactive leadership vision, where public health leaders move beyond passive adoption to collaborate with AI specialists to co-create, co-design, co-develop, and co-deploy tools and resources tailored to the unique needs of public health practice. Call to action: Public health professionals can co-innovate in shaping AI evolution to ensure equitable, ethical, and value-based public health. Full article
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