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2nd Edition: Pregnancy and Perinatal Health
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2nd Edition: Pregnancy and Perinatal Health

A special issue of Healthcare (ISSN 2227-9032).

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 10406

Special Issue Editors

Prof. Dr. Claude Billeaud

E-Mail Website1 Website2
Guest Editor
Hôpital des Enfants, CHU Pellegrin, 33076 Bordeaux, France
Interests: disciplines; pediatrics; nutrition and dietetics; skills and expertise; pregnant nutrition; transfattyacids; human; milk; neonatology; neonatal medicine; prenatal diagnosis; neonatal resuscitation; infant; nutrition-materna
Special Issues, Collections and Topics in MDPI journals
Dr. Virginie Rigourd

E-Mail Website
Guest Editor
1. Neonatology Necker Enfants Malades, 75015 Paris, France
2. Milk Bank Necker Enfants Malades, 75015 Paris, France
Interests: breastfed; human milk; human milk bank; breastfeeding; COVID-19
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

It is my pleasure to announce the launch of a new Special Issue of Healthcare, “Pregnancy and Perinatal Health”. This is, of course, a broad subject which covers all the pathologies of pregnancy that have an impact on the fetus, as well as all the diseases of fetuses and newborns. Some examples of pathologies of pregnancy and perinatal health include: 

  1. Perinatal Hematology:
    • Point on rhesus anemia;
    • Point on neonatal thrombocytopenia;
    • Point on leukemia and oncology in pregnant women;
    • Point on leukemia and oncology in neonate;
    • Point on neonatal hemophilia.
  2. Donation in Perinatology:
    • Donation—a philosopher's perspective;
    • Donation of human milk;
    • Cord blood donation and use;
    • Oocyte, embryo, and sperm donation;
    • Loan of uterus.
  3. Diseases in pregnancy that affect the newborn:
    • Diabetes in pregnant women and newborns;
    • Maternal myopathies and newborns;
    • Myasthenia gravis in newborns;
    • Maternal metabolic diseases in newborns;
    • COVID-19 in pregnant mothers and neonatal care;
    • Congenital malformations (with antenatal diagnostic). 

Kind Regards
Prof. Dr. Claude Billeaud
Dr. Virginie Rigourd
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Healthcare is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pregnancy
  • fetus
  • neonatal health
  • nutrition
  • lipids
  • protein
  • human milk
  • infections: virus, bacterial, congenital malformations (with antenatal diagnostic)
  • diseases of nutrition during pregnancy and/or neonatal diseases
  • human milk
  • human milk banking
  • human milk donation
  • cord blood donation

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Published Papers (4 papers)

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Research

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12 pages, 999 KiB  
Article
Convergent Validity of the Edinburgh Postnatal Depression Scale and the Patient Health Questionnaire (PHQ-9) in Pregnant and Postpartum Women: Their Construct Correlations with Functional Disability
by Manit Srisurapanont, Awirut Oon-arom, Chawisa Suradom, Suchaya Luewan and Suttipong Kawilapat
Healthcare 2023, 11(5), 699; https://doi.org/10.3390/healthcare11050699 - 27 Feb 2023
Cited by 5 | Viewed by 3121
Abstract
This study aimed to evaluate the convergent validity of the Edinburgh Postnatal Depression Scale (EPDS) and the Patient Health Questionnaire (PHQ-9) in Thai pregnant and postpartum women, using the 12-item WHO Disability Assessment Schedule (WHODAS) as the reference standard. Participants completed the EPDS, [...] Read more.
This study aimed to evaluate the convergent validity of the Edinburgh Postnatal Depression Scale (EPDS) and the Patient Health Questionnaire (PHQ-9) in Thai pregnant and postpartum women, using the 12-item WHO Disability Assessment Schedule (WHODAS) as the reference standard. Participants completed the EPDS, PHQ-9, and WHODAS during the third trimester of pregnancy (over 28 weeks in gestational age) and six weeks postpartum. The sample included 186 and 136 participants for the antenatal and postpartum data analyses, respectively. The antenatal and postpartum data showed moderate correlations between both the EPDS and the PHQ-9 scores and the WHODAS scores (Spearman’s correlation coefficients = 0.53–0.66, p < 0.001). The EPDS and PHQ-9 were moderately accurate in distinguishing disability (WHODAS score ≥ 10) from non-disability (WHODAS score < 10) in pregnant and postpartum participants, but the area under the curve of the PHQ-9 receiver operating characteristic curves in postpartum participants was significantly larger than that of the EPDS, with a difference (95% CI; p-value) of 0.08 (0.16, 0.01; p = 0.044). In conclusion, the EPDS and PHQ-9 are valid for assessing PND-related disability in pregnant and postpartum women. The PHQ-9 may perform better than the EPDS in distinguishing disability from non-disability in postpartum women. Full article
(This article belongs to the Special Issue 2nd Edition: Pregnancy and Perinatal Health)
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18 pages, 384 KiB  
Article
Foreign Nationality, Family Psychiatry History and Pregestational Neoplastic Disease as Predictors of Perinatal Depression in a Cohort of Healthy Pregnant and Puerperal Women during the COVID-19 Pandemic
by Laura Orsolini, Simone Pompili, Antonella Mauro and Umberto Volpe
Healthcare 2023, 11(3), 428; https://doi.org/10.3390/healthcare11030428 - 2 Feb 2023
Cited by 1 | Viewed by 2105
Abstract
Background: Perinatal depression (PND) represents one of the most common mental disorders in the pregnancy and/or postpartum period, with a 5–25% prevalence rate. Our aim was to investigate predictors associated with PND in a cohort of pregnant and puerperal women based in an [...] Read more.
Background: Perinatal depression (PND) represents one of the most common mental disorders in the pregnancy and/or postpartum period, with a 5–25% prevalence rate. Our aim was to investigate predictors associated with PND in a cohort of pregnant and puerperal women based in an Italian setting during the COVID-19 pandemic. Methods: We retrospectively recruited 199 (55 pregnant and 144 puerperal) women, afferent to our Perinatal Mental Outpatient Service of Ancona (Italy). Participants were administered an ad hoc case-report form, Whooley Questions (WQ), the General Health Questionnaire-12 (GHQ-12), the Stress Holmes-Rahe scale (HR) and the Edinburgh Postnatal Depression Scale (EPDS). Results: Around 10% of the sample had a confirmed PND. Being a foreigner woman (RR = 3.8), having a positive psychiatric family history (RR = 5.3), a pre-pregnancy medical comorbidity (RR = 1.85) and a comorbid medical illness occurring during the pregnancy (RR = 2) were much likely associated with PND. Multiple linear regression analysis demonstrated that GHQ, medium- and high-risk at the HR, foreign nationality, positive family psychiatric history, and neoplastic disease before conception significantly predicted EPDS [F(1, 197) = 10.086, R2 = 0.324, p < 0.001]. Limitations: The sample size, poor heterogeneity in terms of socio-demographic, clinical and gynecological-obstetric characteristics, the cross-sectional design of the study. Conclusions: Our study showed a set of predictors associated with a higher risk for the PND onset, including gestational and pregestational medical disease. Our findings outline the need to screen all fertile women, particularly in gynecological and medical settings, in order to identify at-risk women for PND and promptly suggest a psychiatric consultation. Full article
(This article belongs to the Special Issue 2nd Edition: Pregnancy and Perinatal Health)

Review

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14 pages, 481 KiB  
Review
Pollutants in Breast Milk: A Scoping Review of the Most Recent Data in 2024
by Raphaël Serreau, Yasmine Terbeche and Virginie Rigourd
Healthcare 2024, 12(6), 680; https://doi.org/10.3390/healthcare12060680 - 18 Mar 2024
Cited by 3 | Viewed by 2995
Abstract
Perinatal exposure to pollutants, including persistent organic pollutants (POPs) and heavy metals, poses significant risks to both mothers and children, marking this period as highly vulnerable. Despite the well-acknowledged benefits of breastfeeding, there exists a gap in comprehensive understanding regarding the impact of [...] Read more.
Perinatal exposure to pollutants, including persistent organic pollutants (POPs) and heavy metals, poses significant risks to both mothers and children, marking this period as highly vulnerable. Despite the well-acknowledged benefits of breastfeeding, there exists a gap in comprehensive understanding regarding the impact of environmental pollutants on breast milk, underscoring the critical need for this study. Our research addresses this gap by exploring the intersection of environmental health and lactation, situated within the broader ‘One Health’ concept, thus contributing a novel perspective to the existing body of knowledge. This scoping review aims to examine recent research on the persistent presence of organic pollutants (POPs) and heavy metals in breast milk, thereby elucidating the environmental setting’s impact on milk quality. We seek to highlight the innovative angle of our study by emphasizing the ‘One Health’ concept, which has not been thoroughly explored in the context of lactation and environmental pollutants. We performed a scoping review, consulting two online databases to identify articles published from 1995 to 2023 that reported on pollutants in breast milk, using the PRISMA checklist. This methodological approach underlines the comprehensive and up-to-date nature of our literature review, ensuring the relevance and timeliness of our findings. From a total of 54 relevant articles, findings indicate that POPs are present in higher concentrations in breast milk the longer the lactation period. These findings highlight the persistent and bioaccumulative nature of such contaminants, offering new insights into their long-term implications for maternal and infant health. This exposure does not appear time-sensitive, suggesting pollutants accumulated in maternal fat compartments can be excreted into human milk years after exposure, a novel finding that underscores the importance of considering long-term environmental exposures in lactation research. The presence of POPs and heavy metals in both infant formula and maternal milk underscores a critical need for further comparative studies to understand the health implications better. Our discussion extends the current dialogue on the safety of breastfeeding in polluted environments, providing a new framework for assessing risks and benefits. While breastfeeding remains the WHO-recommended nutrition for optimal infant growth, the findings emphasize the importance of continued risk reduction policies to protect mothers and infants from environmental contaminants in breast milk. Our conclusion calls for an integrated approach, combining public health, environmental science, and clinical practice to develop effective strategies for reducing exposure to environmental pollutants. This multidisciplinary perspective is a significant contribution to the field, paving the way for future research and policy development. Full article
(This article belongs to the Special Issue 2nd Edition: Pregnancy and Perinatal Health)
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Other

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9 pages, 724 KiB  
Case Report
Hamman’s Syndrome after Vaginal Delivery: A Case of Postpartum Spontaneous Pneumomediastinum with Subcutaneous Emphysema and Review of the Literature
by Kristina Olafsen-Bårnes, Marte Mari Kaland, Karol Kajo, Lars Jakob Rydsaa, Jozef Visnovsky and Pavol Zubor
Healthcare 2024, 12(13), 1332; https://doi.org/10.3390/healthcare12131332 - 3 Jul 2024
Cited by 1 | Viewed by 1277
Abstract
Hamman’s syndrome is a rare condition that mostly affects young males, often with a predisposition to asthma. It includes the presence of free air in the mediastinum and subcutaneous emphysema with no other underlying cause such as trauma, infection, or administration of any [...] Read more.
Hamman’s syndrome is a rare condition that mostly affects young males, often with a predisposition to asthma. It includes the presence of free air in the mediastinum and subcutaneous emphysema with no other underlying cause such as trauma, infection, or administration of any sort of mask support with hyperpressure. It occurs spontaneously and often in association with a prolonged Valsalva maneuver. This might explain why there are some cases of Hamman’s syndrome among young females giving birth. Here, we present a case report of a 24-year-old non-smoker primigravida with Hamman’s syndrome. She presented with symptoms a few hours after an uncomplicated vaginal delivery at 40 + 1 weeks of pregnancy where the active phase of labor lasted for three hours with normal progress. The second stage lasted for 30 min, with no signs of distress on CTG. The symptoms (pain in the right ear, swelling and pain in the neck, chest tightness, shortness of breath, dysphagia, odynophagia, and pain in the upper thorax on the right side) and objective findings as subcutaneous crepitations in the neck, parasternal region, right axillary fossa, clavicle and over the chest resolved spontaneously after a few days of observation and conservative management. We also give a systemic review of reported cases since 2000 to provide an overview of the pathomechanism, symptoms, diagnostics, treatment, and management of this condition. Hamman’s syndrome is a rare, usually benign, but potentially serious complication that can occur during the second stage of labor. Diagnostics include inquiring about typical symptoms, clinical examination, and chest x-ray or CT scan. Treatment is usually conservative with oxygen, bronchodilators, and pain relief. The recurrence rate is low and there is no contraindication to vaginal delivery in future pregnancies. However, it is suggested that physicians and midwives be cautious and consider a low threshold for instrumental delivery or cesarean section to avoid excessive Valsalva maneuvers. Full article
(This article belongs to the Special Issue 2nd Edition: Pregnancy and Perinatal Health)
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