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Treatment and Healthcare of Musculoskeletal Disorders
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Treatment and Healthcare of Musculoskeletal Disorders

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Health Care Sciences & Services".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 1734

Special Issue Editor

Dr. Youngsook Bae

E-Mail Website
Guest Editor
Department of Physical Therapy, College of Health Science, Gachon University, 191, Hambangmoe-ro, Yeonsu-gu, Incheon 21936, Republic of Korea
Interests: physical therapy

Special Issue Information

Dear Colleagues, 

Since musculoskeletal disorders are closely related to quality of life, interest in the treatment and management of musculoskeletal disorders is increasing.

Appropriate treatment and management interventions and programs related to musculoskeletal disorders are expected to contribute significantly to catalyzing new developments in the treatment of musculoskeletal disorders in diverse communities.

This special issue aims to publish original studies and reviews of randomized and non-randomized controlled trials and original studies or reviews of musculoskeletal disorders in the treatment and management of musculoskeletal disorders in diverse populations.

It focuses on multifaceted approaches (treatments) to improving musculoskeletal disorders and quality of life. We invite you to submit original research papers, case reports and reviews. In addition to the keywords below, please submit works addressing topics in all fields related to musculoskeletal treatment and intervention.

Dr. Youngsook Bae
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • health and quality of life
  • geriatric musculoskeletal disorders
  • physical therapy
  • manual therapy
  • therapeutic exercise
  • electrophysical modalities
  • neurologic disorder

Published Papers (1 paper)

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Research

11 pages, 2248 KiB  
Article
Triptolide Attenuates Muscular Inflammation and Oxidative Stress in a Delayed-Onset Muscle Soreness Animal Model
by Che-Chia Hsu, Chin-Chuan Tsai, Po-Yen Ko, Ting-Hsien Kwan, Ming-Yie Liu, Po-Ting Wu and I-Ming Jou
Int. J. Environ. Res. Public Health 2022, 19(24), 16685; https://doi.org/10.3390/ijerph192416685 - 12 Dec 2022
Cited by 3 | Viewed by 1388
Abstract
Delayed-onset muscle soreness (DOMS) is associated with exercise-induced muscle damage and inflammation, which is mainly caused by prolonged eccentric exercise in humans. Triptolide, an extract from the Chinese herb Tripterygium wilfordii Hook F, has been used for treating autoimmune and inflammatory diseases in [...] Read more.
Delayed-onset muscle soreness (DOMS) is associated with exercise-induced muscle damage and inflammation, which is mainly caused by prolonged eccentric exercise in humans. Triptolide, an extract from the Chinese herb Tripterygium wilfordii Hook F, has been used for treating autoimmune and inflammatory diseases in clinical practice. However, whether triptolide attenuates acute muscle damage is still unclear. Here, we examined the effect of triptolide on carrageenan-induced DOMS in rats. Rats were injected with 3% of carrageenan into their muscles to induce acute left gastrocnemius muscular damage, and triptolide treatment attenuated carrageenan-induced acute muscular damage without affecting hepatic function. Triptolide can significantly decrease lipid hydroperoxide and nitric oxide (NO) levels, proinflammatory cytokine production, and the activation of nuclear factor (NF)-ĸB, as well as increase a reduced form of glutathione levels in carrageenan-treated rat muscles. At the enzyme levels, triptolide reduced the inducible nitric oxide synthase (iNOS) expression and muscular myeloperoxidase (MPO) activity in carrageenan-treated DOMS rats. In conclusion, we show that triptolide can attenuate muscular damage by inhibiting muscular oxidative stress and inflammation in a carrageenan-induced rat DOMS model. Full article
(This article belongs to the Special Issue Treatment and Healthcare of Musculoskeletal Disorders)
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