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Advances in Obstetrics and Neonatology
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Advances in Obstetrics and Neonatology

A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section "Reproductive Health".

Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 6467

Special Issue Editor

Dr. Dominik Dłuski

E-Mail Website
Guest Editor
Department of Obstetrics and Perinatology, Medical University of Lublin, 20-954 Lublin, Poland
Interests: pregnancy; GDM; hypertension; endometriosis; ovarian tumor; preterm delivery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are currently organizing a Special Issue entitled "Advances in Obstetrics and Neonatology" in the International Journal of Environmental Research and Public Health. For detailed information on the journal, please visit https://www.mdpi.com/journal/ijerph.

Obstetrics is a very dynamic field of medicine, which cannot exist without working closely with neonatology. Researchers and practitioners in these fields are searching for advances in management, including diagnosis, prevention and treatment. Developing strategies for reducing the risk factors of adverse pregnancy outcomes and acute and long-term complications, as well as understanding the cost of possible future management is crucial. This Special Issue is open to submissions concerning the two aforementioned medical specializations, with a focus on recent and novel topics. The keywords listed below provide an outline of some of the possible areas of interest.

Dr. Dominik Dłuski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pregnancy
  • pregnancy complications
  • cost of management
  • neonatology
  • treatment
  • prevention
  • adverse pregnancy outcomes
  • epidemiology
  • infections
  • risk factors
  • acute complications
  • long-term complications
  • fetus
  • neonate

Published Papers (3 papers)

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Research

13 pages, 1263 KiB  
Article
Tackling Neonatal Sepsis—Can It Be Predicted?
by Špela But, Brigita Celar and Petja Fister
Int. J. Environ. Res. Public Health 2023, 20(4), 3644; https://doi.org/10.3390/ijerph20043644 - 18 Feb 2023
Cited by 1 | Viewed by 1968
Abstract
(1) Background: Early signs of sepsis in a neonate are often subtle and non-specific, the clinical course rapid and fulminant. The aim of our research was to analyse diagnostic markers for neonatal sepsis and build an application which could calculate its probability. (2) [...] Read more.
(1) Background: Early signs of sepsis in a neonate are often subtle and non-specific, the clinical course rapid and fulminant. The aim of our research was to analyse diagnostic markers for neonatal sepsis and build an application which could calculate its probability. (2) Methods: A retrospective clinical study was conducted on 497 neonates treated at the Clinical Department of Neonatology of the University Children’s Hospital in Ljubljana from 2007 to 2021. The neonates with a diagnosis of sepsis were separated based on their blood cultures, clinical and laboratory markers. The influence of perinatal factors was also observed. We trained several machine-learning models for prognosticating neonatal sepsis and used the best-performing model in our application. (3) Results: Thirteen features showed highest diagnostic importance: serum concentrations of C-reactive protein and procalcitonin, age of onset, immature neutrophil and lymphocyte percentages, leukocyte and thrombocyte counts, birth weight, gestational age, 5-min Apgar score, gender, toxic changes in neutrophils, and childbirth delivery. The created online application predicts the probability of sepsis by combining the data values of these features. (4) Conclusions: Our application combines thirteen most significant features for neonatal sepsis development and predicts the probability of sepsis in a neonate. Full article
(This article belongs to the Special Issue Advances in Obstetrics and Neonatology)
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10 pages, 1924 KiB  
Article
The Association of IL-17 and PlGF/sENG Ratio in Pre-Eclampsia and Adverse Pregnancy Outcomes
by Dorota Darmochwal-Kolarz and Anita Chara
Int. J. Environ. Res. Public Health 2023, 20(1), 768; https://doi.org/10.3390/ijerph20010768 - 31 Dec 2022
Cited by 1 | Viewed by 1572
Abstract
The aim of the study was to assess the role of concentrations of interleukin-17 (IL-17), placental growth factor (PlGF) and soluble endoglin (sENG), as well as the PlGF/sENG ratio in pregnancy complicated by pre-eclampsia (PE) and normal pregnancy. The concentrations of IL-17, PlGF [...] Read more.
The aim of the study was to assess the role of concentrations of interleukin-17 (IL-17), placental growth factor (PlGF) and soluble endoglin (sENG), as well as the PlGF/sENG ratio in pregnancy complicated by pre-eclampsia (PE) and normal pregnancy. The concentrations of IL-17, PlGF and sENG were measured with the use of immunoenzymatic methods. The concentrations of IL-17 were significantly higher in PE patients when compared to control patients. In the group of patients with PE, the levels of IL-17 positively correlated with systolic blood pressure. On the other hand, IL-17 negatively correlated with neonatal birth weight. The concentrations of PLGF were significantly lower and sENG significantly higher in studied patients when compared to controls. The PlGF/sENG ratio in the PE group was significantly lower when compared to healthy third trimester pregnant patients. In the study group, negative correlations were observed between the sENG concentrations and thrombocyte levels. The higher concentrations of IL-17 in PE could suggest its role as an inflammatory agent in the pathogenesis of the syndrome. Moreover, the negative correlation between IL-17 and a neonatal birth weight could suggest the role of the cytokine in the development of fetal growth restriction (FGR) associated with PE. It seems possible that IL-17 can be a useful marker of the risk of FGR in pregnancy complicated by PE. Furthermore, the results suggested the potential role of sENG and the PlGF/sENG ratio in the prediction of adverse outcomes such as HELLP syndrome and DIC. Full article
(This article belongs to the Special Issue Advances in Obstetrics and Neonatology)
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14 pages, 1345 KiB  
Article
Effect of Flexible Sacrum Position on Maternal and Neonatal Outcomes in Public Health Facilities, Amhara Regional State, Ethiopia: A Quasi-Experimental Study
by Marta Berta Badi, Solomon Mekonnen Abebe, Mulat Adefris Weldetsadic, Kyllike Christensson and Helena Lindgren
Int. J. Environ. Res. Public Health 2022, 19(15), 9637; https://doi.org/10.3390/ijerph19159637 - 5 Aug 2022
Cited by 2 | Viewed by 2345
Abstract
Restricting women giving birth in health care facilities from choosing the most comfortable position during labor and birth is a global problem. This study was aimed to examine the effect of flexible sacrum birth positions on maternal and neonatal outcomes in public health [...] Read more.
Restricting women giving birth in health care facilities from choosing the most comfortable position during labor and birth is a global problem. This study was aimed to examine the effect of flexible sacrum birth positions on maternal and neonatal outcomes in public health facilities in Ethiopia’s Amhara Region. A non-equivalent control group post-test-only design was employed at public health facilities from August to November 2019. A total of 1048 participants were enrolled and assigned to intervention or control groups based on their choice of birth position. Participants who preferred the flexible sacrum birth position received the intervention, while participants who preferred the supine birth position were placed in the control group. Data were collected using observational follow-up from admission to immediate postpartum period. Log binomial logistic regression considering as treated analysis was used. Of the total participants, 970 women gave birth vaginally, of whom 378 were from the intervention group, and 592 were from the control group. The intervention decreased the chance of perineal tear and poor Apgar score by 43 and 39%, respectively. The flexible sacrum position reduced the duration of the second stage of labor by a mean difference of 26 min. Maternal and newborn outcomes were better in the flexible sacrum position. Full article
(This article belongs to the Special Issue Advances in Obstetrics and Neonatology)
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