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New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices

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A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601).

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 14477

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Prof. Dr. Sang Hun Kim

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Department of Anesthesiology and Pain Medicine, Chosun University Hospital, 365 Pilmun-daero, Dong-Gu, Gwangju 61453, Korea
Interests: acute pain management; chronic pain management; patient’s safety; novel medicines and medical devices; clinical researches
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Special Issue Information

Dear Colleagues,

In this Special Issue of the International Journal of Environmental Research and Public Health, entitled New Advance in Anesthesiology in Pain Management, Medicine, and Medical Devices, I want to touch on a wide range of topics related to this title in the fields of anesthesia and pain medicine.

There is an increasing demand for the active and effective management of pain related to certain diseases as well as surgical anesthesia, but the reality is that many patients are not receiving satisfactory management. In particular, it is necessary to present research results on new effective drugs or various combination therapies to manage certain diseases where severe chronic pain persists and is not well controlled by existing drugs. In addition, many new medicines and medical devices for anesthesia management have been developed and introduced. To use them more effectively, additional studies on their safety, effectiveness, and applications should be supported.

This issue will provide evidence on acute and chronic pain in numerous conditions, the usefulness of new or current medicines or devices, and future directions for research in these fields. Based on all the above, it is my pleasure to announce this Special Issue entitled New Advance in Anesthesiology in Pain Management, Medicine, and Medical Devices. I welcome any papers on any subject that is appropriate for this Special Issue. Meta-analyses, reviews, and original articles are welcome.

Prof. Dr. Sang Hun Kim
Guest Editor

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Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Environmental Research and Public Health is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2500 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

acute pain
anesthesiology
chronic pain
safety
effectiveness
novel drugs and medical devices

Published Papers (7 papers)

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Research

10 pages, 951 KiB

Open AccessArticle

Comparison of the Nasal Cavity Guidance Methods’ Effects during Nasotracheal Intubation Using a Preformed Nasotracheal Tube: A Prospective Randomized Controlled Trial

by Joungmin Kim, Eun-A Jang, Dongho Kang, Seonho Moon and Hong-Beom Bae

Int. J. Environ. Res. Public Health 2023, 20(5), 4503; https://doi.org/10.3390/ijerph20054503 - 3 Mar 2023

Cited by 3 | Viewed by 2332

Abstract

Nasotracheal intubation is mainly performed to provide a safe airway during maxillofacial surgeries. Several guiding devices are suggested to facilitate nasotracheal intubation and reduce complications. We attempted to compare intubation conditions during nasotracheal intubation using a nasogastric tube and a suction catheter, which are readily available in operating rooms. In this study, 114 patients undergoing maxillofacial surgery were randomly divided into the nasogastric tube guidance group (NG group) and the suction catheter guidance group (SC group). The primary outcome was the total intubation time. Moreover, the incidence and degree of epistaxis, the position of the tube in the nasal cavity after intubation, and the number of manipulations during intubation in the nasal cavity were investigated. The insertion time from the nostril to the oral cavity and the total intubation time were significantly shorter in the SC group than in the NG group (p < 0.001). The incidence of epistaxis was lower at 35.1% in the NG group and 43.9% in the SC group than the previously reported 60–80%, but there was no statistical difference between the two groups. The use of a suction catheter aid during nasotracheal intubation can be used effectively because it shortens the intubation time and does not increase complications. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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21 pages, 5010 KiB

Open AccessArticle

Impact of Clinical Pharmacist Consultations on Postoperative Pain in Ambulatory Surgery

by Eric Barat, Catherine Chenailler, André Gillibert, Sophie Pouplin, Remi Varin and Vincent Compere

Int. J. Environ. Res. Public Health 2023, 20(5), 3967; https://doi.org/10.3390/ijerph20053967 - 23 Feb 2023

Cited by 3 | Viewed by 1677

Abstract

Post-operative pain is a common symptom of ambulatory surgery. The objective of this study was to evaluate a pain management protocol integrating a pharmacist consultation. We conducted a quasi-experimental, single center, before-after study. The control group was recruited between 1 March and 31 May 2018 and the intervention group between 1 March and 31 May 2019. Outpatients in the intervention group received a pharmacist consultation, in addition to the usual anesthesiologist and nurse consultations. Pharmacist consultations were conducted in two steps: the first step consisted of general open-ended questions and the second step of a specific and individualized pharmaceutical interview. A total of 125 outpatients were included in each group. There were 17% (95% CI 5 to 27%, p = 0.022) fewer patients with moderate to severe pain in the pharmaceutical intervention group compared with the control group, which corresponded to a decrease in the mean pain level of 0.9/10 (95% CI −1.5/10; −0.3/10; p = 0.002). The multivariate analysis did not reveal any confounding factors, showing that only the pharmaceutical intervention could explain this result. This study demonstrates a positive impact of pharmacist consultations on postoperative pain in ambulatory surgery. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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10 pages, 2241 KiB

Open AccessFeature PaperArticle

Comparison of Postoperative Recovery between Balanced and Total Intravenous Anesthesia in Patients Undergoing Off-Pump Coronary Artery Bypass (OPCAB) Surgery: A Prospective, Single-Blind Randomized Study

by Dongho Kang, Minji Kim, Hong-Beom Bae, Seonho Moon and Joungmin Kim

Int. J. Environ. Res. Public Health 2023, 20(3), 2310; https://doi.org/10.3390/ijerph20032310 - 28 Jan 2023

Viewed by 1642

Abstract

Recovery after anesthesia has a significant impact on a patient’s return to daily life. This study was performed to compare the postoperative quality of recovery according to the method of anesthesia administered among patients undergoing OPCAB using the Korean version of the Quality of Recovery-40 (QoR-40K) questionnaire. This single-blind, prospective study (trial number: KCT0004726) was performed using a population of 102 patients undergoing OPCAB under general anesthesia. The patients were randomly assigned to one of two groups using a computer-generated list: a total intravenous anesthesia group (Group T) and a balanced anesthesia group (Group B). The QoR-40K score was measured preoperatively and at 24 and 48 h after extubation. There was no significant difference in the QoR-40K scores between the groups at 24 and 48 h after extubation. In addition, there were no significant differences between groups with respect to any of the five dimensions of QoR-40K at 24 and 48 h after extubation. Finally, there were no differences in the postoperative opioid consumption, time to extubation, or length of hospital stay. In this study, there was no difference in the QoR-40K score at 24 h after extubation between Groups T and B. Therefore, both methods of anesthesia are suitable for use when performing OPCAB. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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9 pages, 483 KiB

Open AccessArticle

Relationship between Arachidonate 5-Lipoxygenase-Activating Protein Gene and Peripheral Arterial Disease in Elderly Patients Undergoing General Surgery: A Retrospective Observational Study

by Sejong Jin, Eun-Ji Choi, Yoon Ji Choi, Won Kee Min, Ju Yeon Park and Seung Zhoo Yoon

Int. J. Environ. Res. Public Health 2023, 20(2), 1027; https://doi.org/10.3390/ijerph20021027 - 6 Jan 2023

Cited by 1 | Viewed by 1397

Abstract

Patients with peripheral arterial disease (PAD) are at a higher risk of developing postoperative complications. Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) plays an important role in atherosclerosis pathogenesis. In this study, the relationship between PAD and several single nucleotide polymorphisms (SNPs) of ALOX5AP (rs17216473, rs10507391, rs4769874, rs9551963, rs17222814, and rs7222842) was investigated in elderly patients undergoing general surgery. The medical records of 129 patients aged > 55 years who underwent elective general surgery between May 2018 and August 2019 were retrospectively reviewed. The A/A in rs17216473, A/A in rs10507391, G/G in rs4769874, and A/A in rs9551963 were calculated as 0 points and the rest as 1 point to define the genetic risk score. The prevalence of PAD tended to increase with higher genetic risk scores (patients had less ALOX5AP gene polymorphism of A/A in rs17216473, A/A in rs10507391, G/G in rs4769874, or A/A in rs9551963) (p = 0.005). Multivariate logistic regression analysis revealed that the genetic risk score (p = 0.009) and age (p = 0.007) were positively correlated with the prevalence of PAD. Genetic polymorphisms of ALOX5AP and age were associated with the prevalence of PAD in this study. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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14 pages, 1022 KiB

Open AccessArticle

The Effects of Vasodilation Induced by Brachial Plexus Block on the Development of Postoperative Thrombosis of the Arteriovenous Access in Patients with End-Stage Renal Disease: A Retrospective Study

by Jonghae Kim, Kihyuk Park, Youngjin Cho and Jaehoon Lee

Int. J. Environ. Res. Public Health 2022, 19(22), 15158; https://doi.org/10.3390/ijerph192215158 - 17 Nov 2022

Viewed by 1388

Abstract

Although brachial plexus block (BPB)-induced vasodilation reduces the incidence of arteriovenous access (AC) thrombosis, BPB cannot completely prevent its development. Therefore, we retrospectively investigated the factors affecting BPB-induced vasodilation and their effects on AC thrombosis development. Ninety-five patients undergoing AC surgery under BPB were analyzed. Vessel diameters were measured before and 20 min after BPB. The surgery abandoned before the BPB placement was performed when the BPB-induced increases in vessel diameters met its indications. Complete occlusive access thrombosis (COAT) was defined as loss of pulse, thrill, or bruit. Fourteen patients (14.7%) developed COAT. The outflow vein was more dilated by BPB than the inflow artery (0.6 versus 0.1 mm in median, p < 0.001). The original surgery plan was changed for seven patients (7.4%). Diabetes mellitus (DM) and ischemic heart disease (IHD) decreased the extent of increases in the inflow artery by −0.183 mm (95% confidence interval [CI] [−0.301, −0.065], p = 0.003) and outflow vein diameters by −0.402 mm (95% CI [−0.781, −0.024], p = 0.038), respectively. However, DM, IHD, and changes in the vessel diameters had insignificant effects on the development of COAT. In conclusion, although DM and IHD attenuate the vasodilating effects of BPB, they do not contribute to the development of COAT. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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11 pages, 1908 KiB

Open AccessArticle

Optimal Insertion Depth of Gastric Decompression Tube with a Thermistor for Patients Undergoing Laparoscopic Surgery in Trendelenburg Position

by Hwa Song Jong, Tae Won Lim and Ki Tae Jung

Int. J. Environ. Res. Public Health 2022, 19(22), 14708; https://doi.org/10.3390/ijerph192214708 - 9 Nov 2022

Cited by 1 | Viewed by 2951

Abstract

Monitoring core temperature is crucial for maintaining normothermia during general anesthesia. Insertion of a gastric decompression tube (GDT) may be required during laparoscopic surgery. Recently, a newly designed GDT with a thermistor for monitoring esophageal temperature has been introduced. The purpose of the present study was to evaluate the optimal insertion depth of a GDT with a thermistor. Forty-eight patients undergoing elective laparoscopic surgery in the Trendelenburg position were included in the study. The GDT was inserted to a depth of nose–earlobe–xiphoid distance (NEX) + 12 cm and withdrawn sequentially, 2 cm at a time, at 5-min intervals. Temperatures of the GDT thermistor were compared with the core temperature of the tympanic membrane (TM) using Bland and Altman analysis. The correlation between optimal insertion depth of the GDT and anatomical distance (cricoid cartilage to the carina, CCD; carina to the left hemidiaphragm, CLHD) was evaluated, and a mathematical model to predict the optimal insertion depth of the GDT with a thermistor was calculated. Temperatures of TM and GDT thermistor at NEX + 4 cm showed good agreement and strong correlation, but better agreement and stronger correlation were seen at the actual location with the most minor temperature differences. The optimal insertion depth of the GDT was estimated as −15.524 + 0.414 × CCD − 0.145 × CLHD and showed a strong correlation with the actual GDT insertion depth (correlation coefficient 0.797, adjusted R² = 0.636). The mathematical formula using CCD and CLHD would be helpful in determining the optimal insertion depth of a GDT with a thermistor. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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11 pages, 773 KiB

Open AccessArticle

Analgesic Effects of Continuous Wound Infusion Combined with Intravenous Patient-Controlled Analgesia for Thoracic Surgery: A Retrospective Study

by Bo Hyun Jang, Keum Young So and Sang Hun Kim

Int. J. Environ. Res. Public Health 2022, 19(11), 6920; https://doi.org/10.3390/ijerph19116920 - 6 Jun 2022

Viewed by 1903

Abstract

Continuous wound infusion analgesia (CWA) with local anesthetics is a loco-regional anesthetic approach for multimodal analgesia management in surgical procedures. This study analyzed whether the combination of intravenous patient-controlled analgesia (PCA) and CWA would be more effective than PCA alone for postoperative analgesia and in preventing chronic postsurgical pain syndrome (PSPS) after thoracic surgeries. We enrolled 166 patients after propensity score matching, the PCA alone (PCA group, n = 83) and the combination of PCA and CWA (PCA-CWA group, n = 83), through a review of electronic medical records. The primary endpoint was the numeric rating scale (NRS) at postoperative days 1, 2, 3, 4, and 5. The secondary endpoint was the presence of PSPS at 3 and 6 months postoperatively. The NRS were lower in the PCA-CWA group than in the PCA group throughout the postoperative period (p < 0.001). The sedation incidence was lower in the PCA-CWA group (1.2%) than in the PCA group (9.6%) (p = 0.034), and there was no significant difference in other postoperative complications or in the incidence of PSPS (p = 1.000). The combination of intravenous PCA and CWA is an effective postoperative analgesic modality for thoracic surgery. Full article

(This article belongs to the Special Issue New Advance in Anesthesiology on Pain Management, Medicine and Medical Devices)

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