Molecular Mechanisms of Dietary Compounds in Cancer Management

Dear Colleagues,

An intense rhythm of life, stress or other unfavorable situations can lead to the disruption of homeostasis in the human body. In addition, the prolonged lifespan, compared to previous centuries, increased the incidence of chronic non-communicable diseases. Under these circumstances, neoplastic transformation remains one of the biggest challenges of this century. Preventing carcinogenesis or finding therapeutic cures represents a responsibility for all of us working in the biomedical fields. This disease often develops due to high heterogeneity and the ability of the most resistant clones to survive. Moreover, neoplastic transformation can spread in the entire body and behave as a systemic disease. Stopping the proliferating signals and the ability of the transformed cells to resist death, invade, metastasize or induce angiogenesis represent the potential targets in cancer management. Somewhere in this complex tapestry, natural products or dietary compounds can bring their benefit in releasing from the burden of this disease.

The Special Issue welcomes all types of studies dedicated to investigating the molecular mechanisms of the neoplastic transformation and its relationship with dietary compounds.

Prof. Dr. Maria Magdalena Mocanu
Dr. Alexandru Filippi
Guest Editors

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• dietary compounds
• cancer prevention
• cancer therapy
• signaling pathways
• heterogeneity
• multidrug resistance
• cancer stem cells
• genetic modifications in cancer
• cancer and inflammation
• viral infection in cancer
• tumor microenvironment