Transporters in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 January 2025 | Viewed by 67
Special Issue Editor
Interests: transporters; regulation; kidneys; drugs; toxicity; physiology; polarity; chemotherapeutics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Transporter proteins play a crucial role in maintaining cellular physiology, metabolism, and signaling by facilitating the movement of water and various solutes, such as inorganic and organic ions, hormones, amino acids, sugars, and other substances, across biological membranes. Additionally, they can mediate the transport of environmental toxins, xenobiotics, and drugs across the plasma membrane. This is particularly important for hydrophilic drugs, which often rely on transporters to reach their target sites or be effectively cleared from the body. Alterations in the function or expression of these transporters can lead to cellular dysfunction and contribute to the development of diseases. Conversely, the presence of disease can also impact the expression and function of transporters. For instance, the dysregulation of the renal epithelial sodium channel can increase sodium and water reabsorption in the kidneys, leading to hypertension, as observed in Liddle's syndrome, while changes in transporter expression can affect drug pharmacokinetics and toxicity.
This Special Issue will compile the latest insights into the role of transporters in health and disease and their pharmacological and toxicological implications. We invite submissions of original research articles and reviews.
Prof. Dr. Giuliano Ciarimboli
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- transporters
- disease
- regulation
- drugs
- toxicity
- signaling
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
