ijms-logo

Journal Browser

Journal Browser

Advances in the Genetics of Female Reproductive Health and Disease

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: closed (28 February 2024) | Viewed by 2713

Special Issue Editor


E-Mail Website
Guest Editor
Laboratory of Biology of Reproduction, Hospital Saint Joseph, 13008 Marseille, France
Interests: oocytes; embryo cryopreservation; embryo culture; reproductive biology

Special Issue Information

Dear Colleagues,

IJMS (International Journal of Molecular Sciences) is proposing a Special Issue entitled “Advances in the Genetics of Female Reproductive Health and Disease”.

This Special Issue summarizes research on genetics and epigenetics of female reproductive disorders, with a special interest in the interaction between genetics and the environment, especially the impact of microbiota. This Special Issue focuses on the pathogenesis and (epi)genetic factors of female infertility, ovarian (premature) aging, and abnormal proliferation of female reproductive tissue like endometriosis and polycystic ovarian syndrome.

This Special Issue aims to publish high-quality manuscripts, with a particular emphasis on the pathophysiology and molecular mechanisms associated with female reproductive disorders and health, opening up new perspectives of care.

Dr. Isabelle Koscinski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • female infertility
  • ovarian aging
  • genetic
  • epigenetic
  • endometriosis

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

12 pages, 2677 KiB  
Article
Mitigating Age-Related Ovarian Dysfunction with the Anti-Inflammatory Agent MIT-001
by Min-Hee Kang, Yu Jin Kim, Min Jeong Cho, JuYi Jang, Yun Dong Koo, Soon Ha Kim and Jae Ho Lee
Int. J. Mol. Sci. 2023, 24(20), 15158; https://doi.org/10.3390/ijms242015158 - 13 Oct 2023
Cited by 2 | Viewed by 2355
Abstract
Ovarian aging is a major obstacle in assisted reproductive medicine because it leads to ovarian dysfunction in women of advanced age. Currently, there are no effective treatments to cure age-related ovarian dysfunction. In this study, we investigated the effect of MIT-001 on the [...] Read more.
Ovarian aging is a major obstacle in assisted reproductive medicine because it leads to ovarian dysfunction in women of advanced age. Currently, there are no effective treatments to cure age-related ovarian dysfunction. In this study, we investigated the effect of MIT-001 on the function of aged ovaries. Young and old mice were utilized in this study. MIT-001 was intraperitoneally administered, and the number of follicles and oocytes was analyzed. Each group was then retrieved for RNA and protein isolation. Total RNA was subjected to mRNA next-generation sequencing. Protein extracts from ovarian lysates were used to evaluate various cytokine levels in the ovaries. MIT-001 enhanced follicles and the number of oocytes were compared with non-treated old mice. MIT-001 downregulated immune response-related transcripts and cytokines in the ovaries of old mice. MIT-001 modulates the immune complex responsible for generating inflammatory signals and has the potential to restore the function of old ovaries and improve female fertility. Full article
(This article belongs to the Special Issue Advances in the Genetics of Female Reproductive Health and Disease)
Show Figures

Figure 1

Back to TopTop