Molecular Strategies to Overcome Antibiotic Resistance in Carbapenem-Producing Bacteria
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 500
Special Issue Editors
Interests: clinical and experimental pharmacology; oncology; clinical pharmacy; clinical trials
Special Issues, Collections and Topics in MDPI journals
Interests: epidemiology of multidrug-resistant pathogens; infection prevention and control; healthcare-associated infections surveillance; public heath; vaccines
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antibiotic resistance, particularly in carbapenem-producing bacteria, presents a critical challenge to global healthcare. The escalation of resistance mechanisms, including the emergence of carbapenemases, has severely limited treatment options, leading to increased morbidity and mortality rates worldwide. Understanding the intricate molecular pathways driving resistance is essential for devising effective therapeutic interventions.
This Special Issue endeavors to comprehensively explore innovative molecular strategies aimed at overcoming antibiotic resistance in carbapenem-producing bacteria. It seeks to advance our understanding of the underlying genetic and biochemical mechanisms driving resistance, with a focus on identifying novel targets for therapeutic intervention. The scope of this collection encompasses a wide array of research topics, including mechanistic studies, drug discovery efforts, and clinical investigations, with the ultimate goal of informing the development of urgently needed antimicrobial therapies.
This Special Issue will showcase pioneering research at the forefront of efforts to combat antibiotic resistance in carbapenem-producing bacteria. Contributions will encompass a diverse range of methodologies, including, but not limited to, genomic and proteomic analyses, the structural elucidation of resistance determinants, innovative drug screening approaches, and clinical trials of novel therapeutics. Emphasis will be placed on studies that offer novel insights into resistance mechanisms and propose transformative solutions with the potential to reshape clinical practice.
Supervised by Prof. Dr. Daniela Calina and Dr Ovidiu Zlatian and assisted by Associate Prof. Dr. Alice Ghenea, we invite submissions of original research articles, comprehensive reviews, and insightful perspectives that significantly advance our understanding of molecular strategies to overcome antibiotic resistance in carbapenem-producing bacteria. Submissions may span basic mechanistic studies, translational research efforts, and clinical investigations, provided they offer substantial scientific merit and contribute to the overarching goals of this Special Issue.
Prof. Dr. Daniela Calina
Dr. Ovidiu Zlatian
Guest Editors
Manuscript Submission Information
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Keywords
- antibiotic resistance
- antimicrobial agents
- bacterial pathogens
- carbapenemases
- genomics
- molecular mechanisms
- therapeutic targets
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