The Role of Neuropeptides and Their GPCRs in the Neuroendocrine System
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 August 2026 | Viewed by 30
Special Issue Editor
Interests: neuroendocrinology; neuropeptides; sex steroids; central nervous system; autonomic nervous system; socio-sexual behaviors; sexual dimorphism in the brain; spinal cord; hypothalamus
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The neuroendocrine system controls vital physiological functions, including homeostasis, growth, reproduction, and stress responses, through complex interactions between the nervous and endocrine systems. At the core of this sophisticated regulatory system are diverse neuropeptides and their target G-protein-coupled receptors (GPCRs).
Neuropeptides are secreted by neuroendocrine cells, particularly in the hypothalamus, and participate in a wide range of physiological functions, including pituitary hormone release control, feeding behavior regulation, circadian rhythm maintenance, and emotional control. The actions of these bioactive substances are mediated through specific GPCRs via signal transduction pathways that activate diverse intracellular signaling cascades.
This Special Issue will share the latest research findings and enhance our understanding of neuropeptide–GPCR systems in the neuroendocrine field, from the molecular to organismal level. We aim to offer innovative insights to help advance this field, from basic research to clinical applications.
Prof. Dr. Hirotaka Sakamoto
Guest Editor
Manuscript Submission Information
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Keywords
- neuropeptides
- G-protein-coupled receptors (GPCRs)
- neuroendocrine system
- signal transduction
- hypothalamus
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