Molecular Aspects of Retinopathy and Protection
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 25 November 2024 | Viewed by 152
Special Issue Editor
2. Department of Ophthalmology, China Medical University Hospital, Taichung 404327, Taiwan
Interests: eye; cataract; eyelid surgery; ophthalmology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Molecular retinopathy studies encompass a wide range of knowledge that includes genetic mutations or biochemical functions that affect the retina’s normal functioning. Advances in molecular biology and genetics have significantly enhanced our understanding of these conditions, allowing for the identification of key pathogenic mechanisms and the development of targeted therapeutic strategies.
Protection against molecular retinopathy involves a multi-faceted approach, incorporating early diagnosis, genetic counseling, lifestyle modifications, and emerging therapies. Genetic screening and molecular diagnostics play a crucial role in identifying at-risk individuals and enabling early intervention. Current protective strategies also focus on mitigating risk factors such as oxidative stress, inflammation, and metabolic dysfunction through pharmacological agents, nutritional supplements, and lifestyle interventions.
Innovative treatments, including gene therapy, stem cell therapy, and the use of neuroprotective agents, are being explored to address the underlying molecular causes of these retinopathies. The goal of these therapies is not only to halt disease progression but also to restore vision and improve the quality of life for affected individuals.
In summary, molecular retinopathy represents a complex interplay of genetic and biochemical factors leading to retinal degeneration. Advances in understanding the molecular underpinnings of these conditions have paved the way for novel protective and therapeutic strategies aimed at preserving vision and enhancing retinal health.
Prof. Dr. Hui-Ju Lin
Guest Editor
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Keywords
- molecular retinopathy
- retinal degeneration
- photoreceptor cells
- oxidative stress
- inflammation
- apoptosis
- neuroprotection
- gene therapy
- antioxidants
- cytoprotecting
- retinal pigment epithelium (RPE)
- angiogenesis
- microglia activation
- mitochondrial dysfunction
- growth factors
- signal transduction
- neurotrophic factors
- retinal vascular disease
- stem cell therapy
- anti-inflammatory agents
- proteomics
- gene expression
- retinal ischemia
- macular degeneration
- retinitis pigmentosa
- endoplasmic reticulum stress
- autophage
- cell signaling pathways
- therapeutic targets
- retinal cell regeneration
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