Rational Design and Synthesis of Bioactive Molecules, 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: closed (20 January 2026) | Viewed by 1223
Special Issue Editor
Interests: bioinorganic chemistry; medicinal chemistry; coordination chemistry; theoretical chemistry; vibrational spectroscopy; drug discovery; pharmacological investigations; biologically active compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The development and application of bio-organic, bioinorganic, coordination chemistry and nanostructured materials in medicine is an emerging field, and novel therapeutic and diagnostic compounds are now having an impact on medical practice. Much attention has focused on designing new structures with the desired composition, improved pharmacological properties and a broader range of activity. The application of new synthetic, analytical, and spectral methodologies and theoretical and drug delivery approaches widely used in drug discovery is beneficial for the development of bioactive substances as therapeutics and diagnostics. These advancements are due to the mutual efforts of chemists, biologists and experts in pharmacology, photophysics and bioimaging.
This Special Issue, entitled “Rational Design and Synthesis of Bioactive Molecules”, focuses on recent advances in this multidisciplinary field. Special emphasis is put on rational design and synthesis, structure determination, bonding, and theoretical, analytical and physicochemical drug discovery strategies, together with the design of novel drug delivery systems related to the biologically relevant applications of a variety of compounds with improved efficiency. The scope of this collection is to review and critically discuss these current developments and provide the reader with up-to-date information on various aspects of this fascinating topic. Original research articles, short communications and reviews highlighting the latest advances in the field will be considered for publication.
Prof. Dr. Irena Kostova
Guest Editor
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Keywords
- synthesis
- structure
- bonding
- reactivity
- chemical properties
- physical properties
- pharmacological activity
- structure–activity relationship
- applications
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