Probiotics in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 25 June 2025 | Viewed by 17
Special Issue Editor
Special Issue Information
Dear Colleagues,
Probiotics are intensively used, and, consequently, they have become the regular, first-choice microbial-based therapy for intestinal dysbiosis. This stems from accumulating scientific evidence confirming their functionality in in vitro, in vivo, and (pre)clinical trials. Their importance also results from the knowledge that probiotic species, by balancing intestinal microbiota, in addition to preventing or treating intestinal disorders, can impact diseases linked to the gut–liver–brain axis and many others. Moreover, documented probiotics activities have been recognized in specialized subjects such as newborns and certain patient groups, such as people with irritable bowel diseases. Therefore, this Special Issue invites all studies describing the molecular mechanisms and/or probiotic cellular structures associated with probiotic–host interactions in health or disease. This includes the molecular patterns by which probiotic strains regulate adhesion and colonization processes, exclude enteropathogens, influence the host metabolism, or exert immunomodulation effects, alongside research using omics approaches to study specific dysbioses, with an emphasis on an integrated multiomics overview of the host and the microbiota to understand the underlying mechanisms during conditions of health and disease. This issue is also dedicated to the importance of a critical approach due to increasing probiotic strains becoming available on the market, inviting articles considering the importance of assuring their safety and quality.
Prof. Dr. Jasna Novak
Guest Editor
Manuscript Submission Information
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Keywords
- probiotic
- microbiota
- quality
- dysbiosis
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