Pain: From Molecular Basis to Therapy

Dear Colleagues,

Pain is a multifaceted and pervasive phenomenon that significantly impacts the quality of life of millions worldwide. Despite considerable advancements in our understanding of its mechanisms, effective management of pain remains a major clinical challenge. Pain can arise from various conditions, including inflammation, nerve damage, and chronic diseases, each involving complex molecular and cellular processes. Advances in molecular biology have provided deeper insights into the pathways and mediators involved in pain signaling, opening new avenues for targeted therapeutic interventions.

This Special Issue, “Pain: From Molecular Basis to Therapy”, aims to present cutting-edge research and comprehensive reviews that delve into the molecular underpinnings of pain. Topics of interest include the identification and characterization of pain-related receptors and ion channels, the role of neurotransmitters and neuromodulators in pain pathways, genetic and epigenetic influences on pain sensitivity, and the interaction between immune cells and neurons in pain. Additionally, we seek contributions that explore innovative therapeutic strategies, including novel pharmacological agents, gene therapy, and non-pharmacological approaches such as neuromodulation and regenerative medicine.

We invite researchers and clinicians to submit original research articles, reviews, and short communications that advance our understanding of the molecular basis of pain and propose novel therapeutic approaches. Through this Special Issue, we aim to foster a comprehensive understanding of pain mechanisms and facilitate the development of more effective pain management strategies.

Dr. Samuel J. Lin
Guest Editor

Manuscript Submission Information

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