Targeting Oxidative Stress for Disease: 2nd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 68
Special Issue Editors
Interests: oxidative stress-induced diseases; natural products; chemoprevention and tumor therapy; bee products and health; radioprotection
Special Issues, Collections and Topics in MDPI journals
2. School of Medicine, Catholic University of Croatia, 10000 Zagreb, Croatia
Interests: neuroprotection; neurotoxicity; neurodegenerative diseases; oxidative stress; polyphenols; neuropharmacology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Oxidative stress (OS) represents the metabolic state of the organism induced by an increase in the amount of reactive oxygen species (ROS). It is most often associated with neurological diseases but also contributes to the pathogenesis of a number of seemingly unrelated disorders, including type 2 diabetes, cancer, aging, heart and acute renal failure, hypertension, preeclampsia, atherosclerosis and coronary disease, asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, glaucoma, osteoporosis, and sexual dysfunction, among others.
This Special Issue aims to provide a comprehensive insight into the understanding of the role of ROS-mediated effects in the physiological, and especially in the pathological processes of diseases’ development. We would like to highlight the possibilities of exploiting OS as a therapeutic approach in the treatment of cancer.
We cordially invite authors to contribute original articles as well as review papers that present advances on the potential of the most relevant dietary antioxidants on redox biology. These include their antioxidant capacity that may affect biomarkers of oxidative stress and inflammation, as well as their role in the regulation of mitochondrial function, cell signaling proteins, ion channels and transporters, and the ubiquitination/proteasome system, preventing the occurrence of numerous pathological processes.
Prof. Dr. Nada Orsolic
Dr. Maja Jazvinšćak Jembrek
Guest Editors
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Keywords
- oxidants and free radical production
- physiological activities of free radicals
- detrimental effects of free radicals on human health
- ROS and ROS-mediated cellular signaling
- pathophysiology of oxidative stress
- biomarkers of oxidative stress
- chronic degenerative diseases
- therapeutic approaches targeting oxidative stress
- biochemical/molecular targets of chronic diseases
- exogenous antioxidants and human health
- flavonoids and redox biology in the pathophysiology of diseases
- pro-oxidative role of antioxidants: double-sided sword
- prooxidant agents in therapy
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