Molecular Bioinformatics in Pediatric Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".
Deadline for manuscript submissions: closed (29 July 2024) | Viewed by 158
Special Issue Editor
Interests: bioinformatics; machine learning; epigenetics; molecular epidemiology; DNA methylation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Pediatric diseases include a large set of disorders affecting children from birth to adolescence. Understanding the underlying molecular mechanisms of these diseases is crucial for developing effective diagnostic tools and therapeutic interventions. Bioinformatics, machine learning, and artificial intelligence have revolutionized pediatric medicine by providing powerful tools to analyze complex biomolecular data and gain insights into disease pathogenesis.
This Special Issue aims to highlight the new developments and applications of bioinformatics methods in pediatric research, including the importance of deciphering the crucial role of in utero and early-life exposures in shaping pediatric and adult health outcomes. We invite researchers to submit manuscripts addressing the following critical areas:
- Genome-wide association studies for the identification of genetic variants associated with pediatric diseases.
- Development of predictive models for disease risk, treatment response, and clinical outcomes using machine learning and artificial intelligence, with a focus on pediatric diseases and incorporating the impact of early-life exposures.
- Elucidating the molecular mechanisms linking in utero and early-life exposures to future disease development using comprehensive omics data (epigenomic, transcriptomic, proteomic, metabolomic, and gut microbiome), with a focus on pediatric populations.
- Development of personalized medicine approaches for pediatric patients.
We encourage submissions of original research articles that highlight the potential of bioinformatics in improving the molecular-level understanding and management of pediatric diseases, emphasizing the profound impact of in utero and early-life exposures on shaping future health trajectories.
Dr. Giovanni Fiorito
Guest Editor
Manuscript Submission Information
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Keywords
- pediatric diseases
- bioinformatics
- in utero and early-life exposures
- multi-omic biomarkers
- personalized medicine
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