Molecular Pathways in Neurodegenerative Pathologies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (10 November 2024) | Viewed by 1906
Special Issue Editor
Interests: neuroinflammation; central nervous system; degeneration; molecular pathways; protein trafficking
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurodegenerative disease (NDDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) are characterized by a multitude of complicated aetiologies. Lastly, the understanding of the physiological biochemical and molecular mechanisms at the basis of NDDs offers a chance to discover and deeply identify various cross-talk mechanisms of neurodegeneration. Varied and complexed pathways lead to the progression of neurodegeneration, including aging, oxidative stress, excitotoxicity, cell and organelles trafficking, as well as degradative processes like autophagy, mitophagy, issues with the proteosome network, and inflammation of the Central Nervous System (CNS). The aim of the current Special Issue is to describe and recognize the paradigm of NDDs pathways by addressing the key role of modulators, kinases, organelles and across NDDs, with a specific spotlight on AD, PD, and ALS.
Dr. Alessia Filippone
Guest Editor
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Keywords
- neurodegenerative diseases
- kinases
- molecular pathways
- inflammation
- markers
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