Liposomes as Membrane Models in Drug-Lipid Interactions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 3133
Special Issue Editor
Interests: liposomes; membrane interactions; topical vehicles
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The pharmacokinetics and pharmacodynamics of a pharmacologically active molecule in the human body presuppose, in some phases, the interaction of these molecules with cell membranes. Drug absorption is generally achieved at the expense of molecules migrating across the lipid bilayer, as well as interaction with intramembrane or intracellular receptors that can condition the mechanism of action.
In this context, studies of the interaction of molecules with the membrane can be performed using liposomes, as these lipid structures have a membrane similar to that of cells and whose composition and complexity can be easily modulated. Natural biological membranes have a complex structure, whereas lipid-based membrane models offer a simple and useful alternative for studying drug–membrane interactions.
This Special Issue intends to make a collection of papers in this field, focusing both on liposomes of different compositions and manufacturers used as membrane models and on the techniques used to study these interactions. It is expected that the conclusions are of interest to the scope of Pharmacology and the Pharmaceutical Industry and that future perspectives will also be discussed.
Authors are kindly invited to submit original papers, communications, and reviews regarding the use of liposomes as membrane models, to be published in this Issue of International Journal of Molecular Sciences.
Dr. Carla Matos
Guest Editor
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Keywords
- liposomes
- membrane interactions
- drug development
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