Cellular and Molecular Biology in the Compromised Neonate
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 4164
Special Issue Editor
Interests: fetal/neonatal development; immune modulation; pharmacological nutrition; plant sterols; cell-based therapies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neonates can face various perinatal injurious events including infections, placental dysfunction, disrupted oxygen supply, and alterations in blood flow and mechanical ventilation, and these injurious events around birth have been identified as important risk factors for the development of adverse outcomes in later life. Although our understanding of the pathophysiological processes in the compromised neonate has increased enormously in recent years, therapeutic options in the clinic to improve neonatal outcome in the perinatal period are still limited. Therefore, there is a great need to improve our understanding of the underlying mechanisms leading to these adverse outcomes upon a bad start in life. This renewed knowledge can then be used to identify new therapeutic targets to improve short- and long-term outcomes of the vulnerable neonate. Therefore, this Special Issue aims to gather high-quality research manuscripts or reviews that focus on the molecular and cellular mechanisms in the course of injurious perinatal events that predispose to postnatal diseases throughout life.
Dr. Tim G. A. M. Wolfs
Guest Editor
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Keywords
- compromised neonate
- infections
- placental dysfunction
- disrupted oxygen supply
- molecular and cellular mechanisms
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