Metabolic Dysfunction-Associated Steatotic Liver Disease: From Basic Research to Clinical Approaches
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 1518
Special Issue Editor
Interests: hepatic steatosis; diabetes and its complications; obesity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health concern, and it is considered the most common cause of chronic liver disease. A positive diagnosis of MASLD is based on the presence of hepatic steatosis coupled with at least one cardiometabolic risk factor and no other distinguishable cause.
MASLD includes a wide range of liver injuries and can lead to severe conditions such as cirrhosis and liver cancer. Its presence is associated with an increased susceptibility to mortality across different causes. Despite the prevalence of MASLD, a specific approved pharmaceutical compound effective for its treatment is still lacking. Being a complex disease involving genetic susceptibility and environmental factors, an ideal treatment approach for MASLD should target various aspects, such as steatosis reduction, improvement in liver functionality, and protection from other comorbidities. For this purpose, it is critical to fully understand the pathogenesis of MASLD, develop new strategies targeting selective pathways for its prevention or delayed progression, and identify risk factors for early diagnosis.
This Special Issue aims to present a collection of articles related to MASLD from basic research to clinical approaches. Comprehensive studies summarizing the latest findings on clinical trials and studies providing new insights into the cellular and molecular mechanisms involved in MASLD are welcome.
Dr. Barbara Toffoli
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolic dysfunction-associated steatotic liver disease (MASLD)
- steatosis
- obesity
- type 2 diabetes mellitus
- therapeutic targets and interventions
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
