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Molecular Advances in Anti-bacterial Polymers

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 1211

Special Issue Editor


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Guest Editor
Massachusetts Institute of Technology, Cambridge, MA, USA
Interests: sustainability; food waste; food safety; climate change; nanotechnology; polymers; microplastics

Special Issue Information

Dear Colleagues,

Welcome to our Special Issue focused on molecular advances in antibacterial polymers. Antimicrobial polymers are important macromolecular structures that could kill pathogenic microorganisms and inhibit their growth activity. They are widely studied in several research areas such as food technology, food packaging, textiles, agriculture and biomedicine. The use of antibacterial polymers will help reduce the amount and frequency of antibiotic use.

Antimicrobial polymers are generally categorized into two types based on how they impart antimicrobial activity. The first are polymers with inherent antimicrobial properties that do not require modification to induce antimicrobial activity. The other type requires modification to achieve antimicrobial activity and can be differentiated by the type of modification. Polymers can be chemically modified to induce antimicrobial activity or used as scaffolds for the addition of organic or inorganic compounds.

The purpose of this Special Issue is to supply a platform for research on the development of antimicrobial polymer exploration and evaluation, starting from their synthesis to their biological evaluation, mechanistic studies and modifications.

Dr. Yagmur Yegin
Guest Editor

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Keywords

  • anti-bacterial polymers
  • polymer synthesis
  • biological evaluation
  • mechanistic studies
  • application of biocide polymers
  • food packaging
  • biocide polymers coatings and surfaces
  • antibiofilm
  • foodborne pathogens
  • smart delivery systems

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Published Papers (1 paper)

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Research

9 pages, 2058 KiB  
Communication
Antimicrobial Activity of Positively Charged Oligopeptides with Theoretical High α-Helix Content against Cutibacterium acnes
by Miyako Yoshida, Saki Hayashi, Tamami Haraguchi, Momoka Ito, Yoshiro Hatanaka, Miki Yoshii, Hiroaki Tatsuoka, Shigemitsu Tanaka and Toshihiro Nagao
Int. J. Mol. Sci. 2024, 25(13), 7445; https://doi.org/10.3390/ijms25137445 - 6 Jul 2024
Viewed by 701
Abstract
Cutibacterium acnes is abundant and commonly exists as a superficial bacteria on human skin. Recently, the resistance of C. acnes to antimicrobial agents has become a serious concern, necessitating the development of alternative pharmaceutical products with antimicrobial activity against C. acnes. To [...] Read more.
Cutibacterium acnes is abundant and commonly exists as a superficial bacteria on human skin. Recently, the resistance of C. acnes to antimicrobial agents has become a serious concern, necessitating the development of alternative pharmaceutical products with antimicrobial activity against C. acnes. To address this need, we evaluated the antimicrobial activity of CKR-13—a mutant oligopeptide of FK-13 with increased net charge and theoretical α-helical content—against C. acnes in modified Gifu Anaerobic Medium broth by determining the minimum inhibitory concentration (MIC). CKR-13 exerted greater antimicrobial activity against C. acnes than FK-13 in the broth at pH 7.0. The antimicrobial activity of CKR-13 with RXM against C. albicans was pH-dependent. The ionization of CKR-13 and pH-dependent growth delay of C. albicans was suggested to be associated with the increase in CKR-13 antimicrobial activity. Full article
(This article belongs to the Special Issue Molecular Advances in Anti-bacterial Polymers)
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