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Diet and Oxidative Stress

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1249

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Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Firenze, 50121 Firenze, Italy
Interests: thrombosis; fibrinogen; oxidative stress; protein structure
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Special Issue Information

Dear Colleagues,

This Special Issue delves into the intricate interplay between diet and oxidative stress, highlighting the pivotal role of dietary choices in shaping the body’s oxidative balance. Oxidative stress, resulting from the imbalance between reactive oxygen species (ROS) production and the body’s antioxidant defenses, is implicated in numerous chronic diseases. This Special Issue aims to elucidate how dietary patterns influence oxidative stress and subsequent health outcomes in the face of the escalating global prevalence of chronic diseases.

This Special Issue will explore the specific roles of dietary components in either contributing to or mitigating oxidative stress. Emphasizing the importance of a well-balanced diet rich in antioxidants like vitamins C and E, beta-carotene, selenium, and zinc, the research contrasts this with diets high in processed foods, refined sugars, and saturated fats, associated with promoting oxidative stress.

The call for contributions extends to various article types, including original research, reviews, brief reports, commentaries, opinions, perspectives, and case reports. Researchers are encouraged to identify novel biomarkers linked to oxidative stress within dietary contexts. The research topic encompasses the exploration into new pathways for understanding diet-related oxidative stress, personalized nutrition through “omics”-based technologies, pharmacological agents influencing redox regulation via diet, and comprehensive studies on the impacts of specific dietary interventions.

In summary, this Special Issue aims to deepen our understanding of the intricate relationship between diet and oxidative stress. By unraveling molecular mechanisms and identifying potential biomarkers, the goal is to pave the way for personalized dietary interventions and contribute to novel therapeutic approaches for addressing oxidative stress-related health concerns.

Dr. Matteo Becatti
Guest Editor

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Keywords

  • diet
  • antioxidants
  • personalized medicine
  • oxidative stress
  • health and disease

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Published Papers (1 paper)

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29 pages, 1033 KiB  
Review
Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread
by Francesca Cuffaro, Edda Russo and Amedeo Amedei
Int. J. Mol. Sci. 2024, 25(12), 6473; https://doi.org/10.3390/ijms25126473 - 12 Jun 2024
Viewed by 1017
Abstract
Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects around 10% of reproductive-age women, significantly affecting fertility. Its prevalence remains elusive due to the surgical confirmation needed for diagnosis. Manifesting with a range of symptoms, including dysmenorrhea, dyschezia, dysuria, dyspareunia, [...] Read more.
Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects around 10% of reproductive-age women, significantly affecting fertility. Its prevalence remains elusive due to the surgical confirmation needed for diagnosis. Manifesting with a range of symptoms, including dysmenorrhea, dyschezia, dysuria, dyspareunia, fatigue, and gastrointestinal discomfort, EM significantly impairs quality of life due to severe chronic pelvic pain (CPP). Psychological manifestations, notably depression and anxiety, frequently accompany the physical symptoms, with CPP serving as a key mediator. Pain stems from endometrial lesions, involving oxidative stress, neuroinflammation, angiogenesis, and sensitization processes. Microbial dysbiosis appears to be crucial in the inflammatory mechanisms underlying EM and associated CPP, as well as psychological symptoms. In this scenario, dietary interventions and nutritional supplements could help manage EM symptoms by targeting inflammation, oxidative stress, and the microbiome. Our manuscript starts by delving into the complex relationship between EM pain and psychological comorbidities. It subsequently addresses the emerging roles of the microbiome, inflammation, and oxidative stress as common links among these abovementioned conditions. Furthermore, the review explores how dietary and nutritional interventions may influence the composition and function of the microbiome, reduce inflammation and oxidative stress, alleviate pain, and potentially affect EM-associated psychological disorders. Full article
(This article belongs to the Special Issue Diet and Oxidative Stress)
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