Monoamine Signalling Pathways as a Target for Pathomechanism of Mental Disorders and Pharmacotherapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 72
Special Issue Editor
Interests: neurobiology; pharmacology; stress; psychiatric disorders
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The monoaminergic system comprises norepinephrine, dopamine, serotonin, and histamine neurotransmitter pathways and is known to regulate arousal, emotion, and memory. On the other hand, the functioning of these pathways is compromised by neuropsychiatric disorders, including depression, schizophrenia, or neurodegenerative diseases. The involvement of the monoamine neurotransmission system in the development of psychiatric disorders is elusive, and available pharmacotherapy counteracting monoaminergic system impairments is not effective enough. The purpose of the Special Issue is to collect original research articles and review papers focused on untangling the complexity of engagement of monoaminergic signal transduction in the pathology of brain function. We aim to bring together the most recent studies that use different experimental approaches in vivo or in vitro broadly related to the following:
- Signalling alterations in psychiatric disorders;
- Regulation of neurotransmission by monoamines/monoamine signalling effectors;
- Psychiatric disorder biomarkers;
- Novel therapies/therapeutic approaches for mental diseases.
Dr. Agnieszka Zelek-Molik
Guest Editor
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Keywords
- monoaminergic system
- psychiatric disorders
- neurotransmission regulation
- biomarkers
- novel therapies
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