Molecular Research on Ischemic Stroke
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 2990
Special Issue Editor
Special Issue Information
Dear Colleagues,
Acute ischemic stroke (AIS) is one of the most common causes of the need for care. A lot of basic and clinical research studies have been conducted on brain protection therapy for AIS. Brain tissue is composed of two major components: various intraparenchymal cellular systems and microcirculatory systems. In the microcirculatory system, secondary microcirculatory disorders, mainly vascular endothelial injury, have been elucidated, and their clinical application to antithrombotic therapy for AIS has been realized. On the other hand, with the recent development of molecular biology and genetic engineering techniques, the focus of research on the pathogenesis of ischemia in the parenchymal cell system has rapidly shifted to the cellular, intracellular organelle, and molecular levels, and many research results have been accumulated. In addition, the establishment of experimental models of ischemia in vitro, the pathophysiology of neuronal cell death such as apoptosis, regeneration of neural tissues, and ischemic tolerance have become of great interest, and the pathogenesis of cerebral ischemia has become one of the most important research topics in the field of neuroscience. This Special Issue of IJMS aims to focus on both basic science and translational research that will lead from molecular biological approaches to AIS to therapies for this condition.
Dr. Ichiro Nakagawa
Guest Editor
Manuscript Submission Information
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Keywords
- Acute ischemic stroke
- Neuronal regeneration
- Ischemic tolerance
- Mitochondrial dysfunction
- Neurovascular unit
