Biology and Pathology of the Human Hair Follicle
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 2467
Special Issue Editor
2. Monasterium Laboratory, Münster, Germany
3. CUTANEON – Skin & Hair Inventions, Hamburg, Germany
4. Centre for Dermatology Research, University of Manchester, Manchester, UK
Interests: hair follicle; hair; skin; keratinocyte
Special Issue Information
Dear Colleagues,
While the most fundamental progress in basic hair biology over the past few decades has arguably been made by studying mutant mouse models, translating this into advances in the clinical management of hair growth or hair pigmentation disorders has been disappointingly slow. In part, this results from the fact that there are substantial but often underestimated or ignored differences between murine and human hair follicles (HFs), their growth controls, and their response to pharmacological intervention, which must be taken into account when extrapolating from mouse-based concepts to the human condition. The current Special Issue will therefore assemble a much-needed compendium of human HF biology that not only synthesizes the essence of what is currently known about human HF physiology and key controls of human hair growth, pigmentation, and HF stem cells, but also pinpoint how human and mouse HFs differ. This is complemented by presenting key principles of human HF pathobiology, by discussing key open questions in translational human hair research, and by delineating preclinical assays that are best suited to answer these.
Prof. Dr. Ralf Paus
Guest Editor
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