Molecular Advances in Blood–Brain Barrier, Blood–Cerebrospinal Fluid Barrier and Cerebrospinal Fluid–Brain Barriers

Dear Colleagues,

The blood–brain barrier (BBB), blood–cerebrospinal fluid (CSF) barrier (BCSFB), and CSF–brain barriers (CSFBBs) regulate the transport of fluids between the central nervous system and the circulating blood or CSF in order to avoid non-selective crossing of ions, molecules, toxins, and cells into the central nervous system. They are composed of endothelial or epithelial cells, connected by tight junctions, which interact with pericytes and astrocytes in their close vicinity. These barriers are highly selective and their disruption may cause numerous diseases such as stroke, multiple sclerosis, or mental disorders. Disruption of these barriers can be triggered by many factors such as hypoxia, inflammation, or intestinal dysbiosis. The knowledge of the mechanisms that maintain or disrupt these barriers as well as the mechanisms that can repair them is critical to maintaining CNS homeostasis and avoid or treat neurologic diseases.

We are pleased to invite you to contribute with your knowledge and research about the BBB, BCSFB and CSFBBs.

This Special Issue aims to collect cutting-edge information on this topic.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: neuroscience, microbiology, immunology, or clinical research with molecular data.

I look forward to receiving your contributions.

Dr. Eva M. Medina-Rodríguez
Guest Editor

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