Molecular Mechanisms of Combined Radiation Injury and Its Therapies
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 March 2020) | Viewed by 2204
Special Issue Editor
Interests: signal transduction; apoptosis; autophagy; cytokine/inflammation storm; acute radiation syndrome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Combined radiation injury (CI) is a serious problem as it is more likely to be encountered than radiation injury (RI) in the real world. CI is defined as radiation exposure that takes place before or after a form of trauma that can be a physical wound, burn, hemorrhage, infection, blasting, bone fracture, or total brain injury, to name but a few examples. It is evident that while RI causes acute radiation syndrome (ARS), CI compounds the effects of ARS, resulting in multiorgan dysfunction and increases in mortality. Although radiation-induced cataracts are not fatal, the subject receives little attention.
The molecular mechanisms of CI are complex and not fully understood. Moreover, there are no radioprotectants, radiomitigators, or therapeutics available for preventing or treating CI because of its complexity. For this Special Issue, we would like to invite original articles or reviews that report on the current progress of molecular mechanisms of CI, CI-induced ARS, delayed effects of CI, and prophylactic drugs and therapeutics for CI, including gene, cell, or combinational therapies targeting bone marrow, gastrointestinal system, endothelium, brain, skin, eye, lung, and kidney.
Dr. Juliann G. Kiang
Guest Editor
Manuscript Submission Information
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Keywords
- hematopoietic syndrome
- gastrointestinal syndrome
- cutaneous syndrome
- brain hemorrhage
- infection
- radiation combined injury
- therapy for radiation combined injury
- microRNA regulation
- signal transduction
- cytokine/inflammation/infection
