Advantage Application of Coordination Complexes in Bio-Chemical Processes
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 4278
Special Issue Editors
2. School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
Interests: coordination polymer; polyoxometalate; protein misfolding; reactive oxygen species
Interests: design, synthesis, and characterization of novel polyoxometalates (POMs); novel POMs as sensors for the recognition and detection of heavy metal ions; studies on the antiviral, antibacterial, or anticancer activity of novel POMs
Special Issue Information
Dear Colleagues,
The application of coordination complexes in various biological systems is a rapidly growing branch of inorganic chemistry and chemical biology. The number of published papers on the biological applications of coordination complexes has doubled in last decade. Research has largely focused on how coordination complexes inhibit bacterial and tumor cell growth. Coordination complexes appear to dispatch their cellular effects by targeting respiratory chains, DNA/RNA or protein structures and functions, the cytoskeleton, and/or by interfering with the ionic transport systems, etc., leading to cell death. However, the mechanisms of action of these compounds remain obscure.
This Special Issue will highlight the latest advances in in vitro and in vivo coordination complexes, such as pure, hybrids, and/or coordination complex-based nanoparticles cluster, film or hydrogel with antitumor, antiviral, and antimicrobial activities and degradation of antibiotics as well as other biological and/or biomedical applications, e.g., in diabetes and neurological diseases. Studies on coordination complexes such as biosensors, artificial enzymes (including catalysts), conformational modulators, etc., used as biological factors, inducers, or markers of specific illnesses are also welcome. Papers addressing biomolecular targets, coordination complexes’ application as ion channels in lipid/cell membranes and transportation of coordination complexes across cell membranes will be considered, as will molecular simulations of all of the abovementioned topics.
Dr. Xiang Ma
Dr. Pengtao Ma
Guest Editors
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Keywords
- coordination complex
- chemical biology
- inorganic Chemistry
- biomedical applications
- bio-chemical processes
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