Molecular Mechanisms of Tendinopathy: Unraveling the Pathogenesis of Tendon Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 2481
Special Issue Editor
Special Issue Information
Dear Colleagues,
Tendinopathy is a multi-factorial tendon and joint disorder characterized by activity-related tendon pain, stiffness, and physical disability. The affected tendon degenerates and finally ruptures. Both conservative and surgical outcomes are unsatisfactory due to its unclear etiopathogenesis.
This Special Issue aims to encourage the study of the molecular mechanisms of tendinopathy and identify novel targets for its management. Both review and original articles focusing on the risk factors, molecular mechanisms, and novel treatment of tendinopathy are welcome. The roles of various risk factors, such as diabetes mellitus, obesity, dyslipidemia, and drugs, in increasing the susceptibility of tendinopathy development are of particular interest in this Special Issue. Factors affecting healing outcomes after tendon reattachment to bone and tendon repair after injury are within the scope of this Special Issue.
Studies on advanced molecular tools, such as various omics techniques, animal models, and new treatments, including cell-based therapy, drugs and biophysical therapies, and novel biomaterials, are encouraged to be submitted to this Special Issue.
Dr. Pauline Po Yee Lui
Guest Editor
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Keywords
- tendinopathy
- tendon pain
- stiffness
- physical disability
- etiopathogenesis
- molecular mechanisms
- tendon reattachment
- tendon repair
- advanced molecular tools
- omics techniques
- biophysical therapies
- novel biomaterials
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