Bioengineering of Natural Molecules for Treatment of Metabolic Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 424
Special Issue Editor
Interests: natural products; obesity; diabetes; metabolism; nanomolecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The prevalence of metabolic disorders has been on the rise worldwide and has reached epidemic proportions. It is estimated that 25% of the global adult population has metabolic alterations. The development of these metabolic disorders is associated with an increased risk of stroke, heart disease, hypertension, dyslipidemia, and type 2 diabetes. Current treatment strategies are often limited in their efficacy.
The search for effective molecules for the treatment of metabolic diseases has increased, and plants may offer potential pharmacological innovative approaches. However, low production levels and the continuous demand of industry for novel molecules with new or superior biological activities are factors that appear to limit the commercialization of plant-derived molecules.
Many natural products need to be upgraded in terms of pharmacokinetic properties, selectivity, and stability for therapeutic use. A novel approach is to create a chemical derivatization of a previously isolated natural product.
This Special Issue addresses molecular and mechanistic research of bioengineered natural molecules, and we invite researchers to contribute original research articles and reviews focused on different strategies of the structural modification of natural molecules for the treatment of metabolic disorders.
Topics of interest include, but are not limited to, the following:- Obesity;
- Diabetes;
- Insulin resistance;
- Inflammation;
- Dyslipidemia;
- Disorders of protein metabolism.
Prof. Dr. Sergio Acín Martínez
Guest Editor
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