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Pulmonary Fibrosis: Molecular Mechanisms and Therapeutic Strategies

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 28 March 2026 | Viewed by 3

Special Issue Editor

Special Issue Information

Dear Colleagues,

Pulmonary fibrosis is a complex and multipathways process which encompasses a broad spectrum of chronic lung diseases including interstitial lung diseases (ILDs). In recent years, the landscape of these diseases has been evolving significantly. The ongoing advancements of precision medicine, along with the increasing application of artificial intelligence, machine learning and genetic profiling as well as the growing use of omics science has deeply reshaped our approach to ILDs. Simultaneously, a deeper understanding of the molecular mechanisms and signalling underlying ILD pathogenesis is emerging, are paving the way for new therapeutic target. All in all, these developments are opening promising advances for earlier diagnosis, personalized treatment strategies, and improved clinical outcomes.

In this Special Issue, we aim at pointing out the pathogenetic mechanisms and signal pathways involved in pulmonary fibrosis and fibrotic interstitial lung diseases, as well as the application of cutting-edge tools and technologies to advance our understanding of their pathobiology.  

We warmly invite to submit original research articles both in vitro and in vivo, systematic or narrative review that explore these critical aspects.

Prof. Dr. Barbara Ruaro
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • machine learning
  • pulmonary fibrosis
  • interstitial lung diseases
  • molecular mechanisms
  • precision medicine

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Published Papers

This special issue is now open for submission.
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