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Natural-Sourced Compounds: Chemical Composition, Biological Activity and Toxicity Assessment

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: closed (30 May 2024) | Viewed by 1318

Special Issue Editors


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Guest Editor
Laboratory of Marine Biotechnologies and Environment (BIOMARE), Department of Biology, Faculty of Sciences, Chouaib Doukkali University (UCD), El Jadida 24000, Morocco
Interests: toxicology; food contaminants; mycotoxins; risk assessment; public health; food microbiology; probiotics; natural resources; valorization; fermentation

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Guest Editor
Functional Ecology and Environmental Engineering Laboratory, Faculty of Science and Technology, Sidi Mohamed Ben Abdellah University, Fez 30050, Morocco
Interests: natural resources; biotechnology; microbiology; polymer chemistry; materials chemistry; environmental science; food science; plant fertilization; animal and human nutrition

Special Issue Information

Dear Colleagues,

Natural-Sourced Compounds (NSCs) obtained from terrestrial and marine origins such as plants, animals, algae, fish and microorganisms, etc., are considered excellent natural sources of biomolecules with diverse and potentially interesting biological activities. The biological activity of such NSCs depends on their chemical composition and biochemical properties. Their most sought-after biological activities are their antimicrobial, antioxidant and pest control properties, as well as their utility as vectors in various nano- or micro-encapsulation biomaterial applications.

Nowadays, there is a significant demand for research pertaining to the identification of biomolecules from NSCs, considering their potential application in various fields against pathogenic and spoilage microorganisms; this particularly includes the medical, cosmetics, agri-food and environmental domains, and their application as biopesticides. Considering that the quality and safety of biomolecules obtained from NSCs have a direct impact on public health, it is imperative to assess their toxicity in order to make a sound decision before they are utilized in any conceivable application.

This Special Issue, entitled "Natural-Sourced Compounds: Chemical composition, Biological activity and Toxicity Assessment", and launched by MDPI’s International Journal of Molecular Sciences (IJMS), aims to publish high-quality research papers describing the chemical composition of natural compounds obtained from different biological sources (plants, animals, microorganisms, marine sources, etc.) that have high added value, fascinating biological activities and provide novel biotechnological solutions. Particular prominence will be given to articles that obtain NSCs from inexhaustible biological sources, particularly microbial and marine resources, and that employ green alternative extraction methods. The submission of articles reflecting toxicity assessments using in vitro models is strongly encouraged and those addressing the application of validated protocols, methods and/or novel recommended approaches are welcome.

Prof. Dr. Abdellah Zinedine
Dr. Faouzi Errachidi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural-sourced compounds
  • marine resources
  • chemical composition
  • biological activity
  • antimicrobial
  • antioxidant
  • green extraction methods
  • toxicity assessment

Published Papers (1 paper)

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Review

20 pages, 1285 KiB  
Review
Bisphenol A—What Do We Know? A Global or Local Approach at the Public Health Risk Level
by Angelika Edyta Charkiewicz, Wioleta Justyna Omeljaniuk and Jacek Nikliński
Int. J. Mol. Sci. 2024, 25(11), 6229; https://doi.org/10.3390/ijms25116229 - 5 Jun 2024
Viewed by 541
Abstract
BPA has demonstrated enormous multisystem and multi-organ toxicity shown mainly in animal models. Meanwhile, the effects of its exposure in humans still require years of observation, research, and answers to many questions. Even minimal and short-term exposure contributes to disorders or various types [...] Read more.
BPA has demonstrated enormous multisystem and multi-organ toxicity shown mainly in animal models. Meanwhile, the effects of its exposure in humans still require years of observation, research, and answers to many questions. Even minimal and short-term exposure contributes to disorders or various types of dysfunction. It is released directly or indirectly into the environment at every stage of the product life cycle, demonstrating its ease of penetration into the body. The ubiquity and general prevalence of BPA influenced the main objective of the study, which was to assess the toxicity and health effects of BPA and its derivatives based on the available literature. In addition, the guidelines of various international institutions or regions of the world in terms of its reduction in individual products were checked. Bisphenol A is the most widely known chemical and perhaps even the most studied by virtually all international or national organizations, but nonetheless, it is still controversial. In general, the level of BPA biomonitoring is still too high and poses a potential threat to public health. It is beginning to be widely argued that future toxicity studies should focus on molecular biology and the assessment of human exposure to BPA, as well as its substitutes. The effects of its exposure still require years of observation, extensive research, and answers to many questions. It is necessary to continue to deepen the knowledge and interest of many organizations, companies, and consumers around the world in order to make rational purchases as well as future choices, not only consumer ones. Full article
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