Neurological Diseases: From Pathogenesis to Molecular Diagnosis and Treatment
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 8
Special Issue Editors
Interests: epilepsy; epileptogenesis; status epilepticus; neuroprotection; antiepileptic drugs; seizures
Special Issues, Collections and Topics in MDPI journals
Interests: Alzheimer; epilepsy; stroke
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurological diseases constitute a large, heterogeneous group of disorders whose common feature is damage to the central nervous system. Their etiology includes mechanisms such as neurodegeneration, vascular changes, autoimmune processes, synaptic transmission disorders, and genetic defects. Frequently, the development of secondary chronic neuroglial inflammation, oxidative stress, and ion and energy homeostasis disorders can also be observed. In the pathogenesis of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, the main role is played by the abnormal accumulation and aggregation of proteins and their toxic effect on nerve cells. In demyelinating diseases, such as multiple sclerosis, pathogenesis is mainly based on autoimmune damage to myelin sheaths. In the case of stroke, cerebral circulation disorders and cell death are observed. The etiology of epilepsy is multifactorial and includes neurotransmitter dysfunction and genetic mutations, as well as metabolic and electrolyte disorders, neurodegenerative processes, and inflammation in the brain.
Thorough knowledge and understanding of the above mechanisms also offer great opportunities for the development of therapies focusing on the pathomechanisms of neurological diseases. Currently, the most dominant form of therapy is pharmacotherapy, but newer strategies also include gene therapies, microRNA expression modulation, monoclonal antibodies, immunotherapies, and regenerative therapies.
Dr. Barbara Miziak
Prof. Dr. Stanisław Jerzy Czuczwar
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Alzheimer's disease
- Parkinson's disease
- Huntington's disease
- epilepsy
- stroke
- neurological diseases
- treatment of neurological diseases
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
