Protein Signal Transduction in the Nucleus
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 20 May 2025 | Viewed by 959
Special Issue Editor
Special Issue Information
Dear Colleagues,
The proteins in the nuclear membrane network not only maintain cell structure, but also regulate specific signal transduction in response to external stimuli. They can interact with signal proteins or transcription factors that enter the nucleus to regulate various life processes. These proteins function as signal regulators. This Special Issue focuses on the network of nuclear inner membrane proteins sharing the LAP2-emerin-MAN1-domain (LEM-D) and nuclear lamina, which are essential for maintaining the cell nuclear structure. The goal is to highlight their potential as significant signal transduction regulators. Research submissions on the interaction between other nuclear membrane proteins and signal-related factors within the nucleus are also welcome. Comprehensive studies of these proteins can help in the prevention of muscle diseases and cancer caused by signal regulation failure and contribute to the search for therapeutic targets for various diseases. This Special Issue aims to present a new paradigm that expands the field of intracellular signal regulation research into the nucleus, and shares systematic research approaches and results at a time when relevant research is increasing.
Dr. Jaekyung Shim
Guest Editor
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Keywords
- inner nuclear membrane protein
- protein network
- LEM-domain proteins
- nuclear lamina
- signal transcription
- transcriptional regulation
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