Gut Microbiota and Nutrition in Human Health (2nd Edition)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 October 2024 | Viewed by 164
Special Issue Editor
Interests: Alzheimer’s disease; insulin resistance; nutritional epidemiology; nutrigenomics; gut microbiome; type 2 diabetes; bioinformatics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the continuation of our previous Special Issue entitled “Gut Microbiota and Nutrition in Human Health”.
The gut microbiome is believed to profoundly influence many metabolic processes of the host human metabolism. This is often the result of neuroactive signals between the brain and the microbiome bidirectionally and is called the gut–brain axis. The gut–brain axis influences the intestinal permeability through the autonomous system to modulate gut microbiota and their products. Such signals may be mediated by small molecules that are byproducts of the metabolism of gut microbiota, or they may be the results of cytokines and neurotransmitters produced in response to gut bacteria. The microbiome is believed to play a causative role in diverse diseases such as obesity, Alzheimer’s disease, cardiovascular disease, some cancers, diabetes, and fatty liver disease. However, a healthy microbiome can prevent such diseases. Diet is known to be a major factor in determining the composition of the gut microbiome by modulating digestive juices and providing prebiotics. Diets can either expand or suppress microbial diversity, the relative composition of the microbiome (Firmicutes/Bacteroidetes ratio), the network of bacteria, or even increase or decrease specific bacteria such as Akkermansia municiphila. Many of the benefits of healthy diets are a consequence of the subsequent actions of the microbiome in response. However, substantial gaps exist in our understanding of the signaling pathways that control microbial responses to dietary inputs and their subsequent signaling to the brain and other organs of the body. This Special Issue seeks to further the understanding of how dietary modulations of the gut microbiome results in human health outcomes in diverse regions of the body.
A wide range of manuscripts will be considered for this Special Issue. We are especially interested in new research in human subjects, but we will also consider animal research that is applicable to humans. High-quality reviews and manuscripts that describe new research methods are also welcome. We will consider any manuscript that provides new and novel information about how human nutrition may contribute to human health or disease prevention through the gut microbiome.
This Special Issue will cover topics related to interactions of diet and lifestyle with the microbiome that result in either beneficial or harmful outcomes for human health. Especially important are the pathways that link nutrition to changes in the microbiome, and how the changes in the microbiome result in signaling by gut-derived changes in inflammatory cytokines, neurotransmitters, and metabolic hormone signals.
Dr. Sunmin Park
Guest Editor
Manuscript Submission Information
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Keywords
- microbiome
- gut
- brain
- obesity
- diabetes
- inflammation
- liver
- nutrition
- probiotic
- prebiotic
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