Innate and Innate-Like Lymphoid Cells: New Populations and Old Tricks
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (29 November 2023) | Viewed by 8947
Special Issue Editor
2. Laboratory of Immunology and Oncology, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-504 Coimbra, Portugal
3. Center of Investigation in Environment, Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal
4. Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal
5. Center for Innovation in Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal
6. Clinical Academic Centre of Coimbra (CACC), 3000-075 Coimbra, Portugal
Interests: immunology; oncology; immunogenetics; transplantation; human genetics; molecular diagnostics; molecular biology; gene expression; R&D
Special Issue Information
Dear Colleagues,
Lymphocytes are the most studied immune cells in both homeostatic and disease conditions. New populations of innate lymphocytes have been described recently: innate lymphoid cells, including natural killer cells, fetal lymphoid tissue inducer (LTi) cells, and innate intraepithelial lymphocytes expressing CD3 chains. Further, innate B cells, such as B-1 cells, marginal zone B (MZB) cells, and follicular B (FOB) cells MZ, have arisen as new key players in early immunity. Similarly, different conventional and unconventional T cells have been studied for their innate-like functions. Activation, differentiation, plasticity, maturation, and effector functions of all these cells depend on the molecular mechanisms responsible for recognition receptor repertoire, balance of signals, and effector functions.
We are accepting research and review articles on the molecular mechanisms of innate and innate-like lymphoid cells in physiology, infection, auto-immunity, transplantation, cancer, and on new therapeutic strategies.
We are preparing a Special Issue with diverse, comprehensive, and complementary views of the molecular mechanisms of innate lymphoid cells.
Dr. Paulo Rodrigues-Santos
Guest Editor
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Keywords
- innate lymphoid cells
- innate-like
- cytokines
- pattern recognition receptors
- danger-associated molecular patterns
- pathogen-associated molecular patterns
- toll-like receptors
- killer immunoglobulin-like receptors
- major histocompatibility complex
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