Biomedical Applications of Mesenchymal Stem Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 156
Special Issue Editors
Interests: adipose-derived stem cells; neural differentiation; conditioned media; schwann cells; olfactory ensheathing cells
Special Issues, Collections and Topics in MDPI journals
Interests: mesenchymal stem cells; cell differentiation; intercellular communication
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mesenchymal stem cells (MSCs) are characterized by their multipotent differentiation ability. In fact, they can give rise to endodermal and ectodermal cells other than those of the mesodermal variety. Moreover, they have antioxidant and anti-inflammatory properties. For these reasons, MSCs can be suitable for cell-based therapeutic strategies, especially in molecular pathologies where pharmacological treatments produce poor results.
The molecular mechanisms of MSC-induced beneficial effects include neurogenesis, osteogenesis, chondrogenesis, and angiogenesis stimulation, as well as immunomodulatory, anti-inflammatory, and antiapoptotic actions. Moreover, the paracrine release of growth factors and cytokines, mainly delivered at damaged regions, may help to restore tissue homeostasis.
This Special Issue entitled “Biomedical Applications of Mesenchymal Stem Cells” focuses on the role of MSCs in damaged tissue repair and its molecular regulatory mechanism. We welcome submissions of original papers and reviews based on results from molecular viewpoints.
Dr. Giuliana Mannino
Dr. Debora Lo Furno
Guest Editors
Manuscript Submission Information
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Keywords
- mesenchymal stem cells
- cell differentiation
- cell therapy
- regenerative medicine
- tissue homeostasis
- cartilage
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