Mitochondrial Bioenergetics in Different Pathophysiological Conditions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 March 2021) | Viewed by 66517
Special Issue Editors
Interests: mitochondrial bioenergetics; oxidative phosphorylation; mitochondrial dysfunction; metabolic regulation; oxidative stress; apoptosis; Alzheimer’s disease; cystic fibrosis
Special Issues, Collections and Topics in MDPI journals
Interests: mitochondrial bioenergetics; mitochondrial metabolism; mitochondrial transport; mitochondrial signaling pathways; mitochondrial dysfunction; neurodevelopmental diseases; oxidative stress; reactive oxygen species; programmed cell death
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Mitochondria are central actors in the bioenergetics of cellular life. They are maternally inherited, multifunctional organelles widely known for generating energy in the form of ATP through the inner membrane mitochondrial respiratory chain complexes that form the functional respirasome. Besides the oxidative phosphorylation process, mitochondrial transport, inter-organelle crosstalk, mitochondrial dynamics, biogenesis and degradation all play a critical role in the efficiency and homeostasis of mitochondrial bioenergetics. Damage to these highly energetic and redox-sensitive organelles can result in an increase in the autophagic removal of the mitochondria (mitophagy) and disruption to the mitochondrial network. Mitochondrial dysfunction is now emerging as a major contributor to the pathogenesis of a broad range of human diseases, directly or indirectly, through a wide spectrum of signaling pathways.
Contributions to this Special Issue will provide new insights into mitochondrial bioenergetics to deepen our understanding of its role in health and disease and reveal novel mitochondria-targeting therapeutic opportunities. Original research articles and topical reviews on these and related topics are welcome in this Special Issue.
Dr. Anna Atlante
Dr. Daniela Valenti
Guest Editors
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Keywords
- mitochondrial ATP generation
- oxidative phosphorylation machinery
- mitochondrial quality control
- mitochondrial dynamic network
- mitogenesis/mitophagy
- mitochondrial signaling
- inter-organelle crosstalk
- mitochondrial dysfunction
- mitochondria-targeting therapeutic strategies
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Related Special Issues
- Mitochondrial Bioenergetics in Different Pathophysiological Conditions 2.0 in International Journal of Molecular Sciences (16 articles)
- Mitochondrial Bioenergetics in Different Pathophysiological Conditions 3.0 in International Journal of Molecular Sciences (9 articles)
- Mitochondrial Bioenergetics in Different Pathophysiological Conditions 4.0 in International Journal of Molecular Sciences (6 articles)