New Molecular Designs for Drugs including Potential Antibiotics
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 3963
Special Issue Editors
Interests: heterocyclic chemistry; synthetic organic chemistry; natural products chemistry; new indole-based scaffolds; synthetic methodologies
Special Issues, Collections and Topics in MDPI journals
Interests: biologically active molecules; medicinal chemistry; organic chemical synthesis; peptidomimetics; novel antimicrobials; biomaterials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Living systems are the source of a diverse range of bioactive chemicals in many different ways. Naturally produced chemicals are of fundamental importance in biological systems and are used to mediate interactions across all levels of biological hierarchy. Natural products have also been the inspiration for semi-synthetic modifications, or as lead platforms for the synthesis of functional analogues targeted against specific receptors. Synthetic methodology allows the design and synthesis of completely new, yet active, “unnatural” structural types. Utilizing modern synthetic organic chemistry and “natural leads”, novel biologically active molecules can be developed for biological properties, including antimicrobial, anti-inflammatory and anticancer properties.
This Special Issue aims to cover a diverse range of synthetic and natural biologically active molecules for potential leads for drug discovery. Contributions from synthetic chemists, medicinal chemists, molecular biologists and pharmacologists are sought for this multi-disciplinary issue. In addition to manuscripts on the latest results, reviews are also encouraged.
Prof. Dr. David StC Black
Prof. Dr. Naresh Kumar
Guest Editors
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Keywords
- design and synthesis of novel biologically active molecules
- new targets for antibiotic discovery
- structure based drug design
- novel scaffolds for drug discovery
- peptide mimics
- cell-to-cell communication (e.g., quorum sensing)
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