Molecular Research on Neuromuscular Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 4368
Special Issue Editor
Special Issue Information
Dear Colleagues,
Neuromuscular diseases are devastating disorders whose prevalence rates are estimated from 1 to 10 per 100,000 people. Sometimes manifesting as early as from birth, they have dire consequences on the quality of life and sometimes life expectancy of patients. More than 400 neuromuscular diseases have been reported so far, which are of various origins: genetic, inflammatory, auto immune, etc.
During the last decade, major advances have been achieved in the comprehension of the pathological mechanisms of neuromuscular diseases, especially through the use of animal models and omics technologies. Thanks to an increasing and deeper understanding of these diseases, new therapeutics, sometimes highly innovative (gene therapy, antisense oligonucleotides, etc.) are currently under trial or already benefit some patients.
However, our understanding of the pathophysiology of neuromuscular diseases, notably of molecular mechanisms, is still incomplete and hinders the setup of novel therapeutic strategies. Current proposed treatments are indeed often mildly efficient, alleviating some but not all symptoms. Further research on the molecular basis of these diseases as well as discovery of novel biomarkers is thus critically needed to develop more effective treatments.
This Special Issue aims to gather research papers and reviews on current developments and the most recent advances in molecular research on neuromuscular diseases and will hopefully benefit the scientific and medical neuromuscular community in their endeavors in both research and therapeutics.
Prof. Dr. Marie-Anne Colle
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neuromuscular disease
- peripheral nervous system
- motor neuron
- neuromuscular junction
- signaling pathways
- key molecular players
- omics
- molecular biomarkers
